Lusutrombopag

Modify Date: 2024-01-02 15:05:09

Lusutrombopag Structure
Lusutrombopag structure
Common Name Lusutrombopag
CAS Number 1110766-97-6 Molecular Weight 591.546
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C29H32Cl2N2O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Lusutrombopag


Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist, used for treatment of chronic liver disease.

 Names

Name Lusutrombopag
Synonym More Synonyms

 Lusutrombopag Biological Activity

Description Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist, used for treatment of chronic liver disease.
Related Catalog
In Vitro Lusutrombopag acts selectively on the human TPO receptor and activates signal transduction pathways that promote the proliferation and differentiation of bone marrow cells into megakaryocytes, thereby increasing platelet levels[1].
References

[1]. Kim ES, et al. Lusutrombopag: First Global Approval. Drugs. 2016 Jan;76(1):155-8.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C29H32Cl2N2O5S
Molecular Weight 591.546
Exact Mass 590.140869
LogP 8.64
Index of Refraction 1.618
Storage condition 2-8℃

 Synonyms

S-888711
Acide (2E)-3-{2,6-dichloro-4-[(4-{3-[(1S)-1-(hexyloxy)éthyl]-2-méthoxyphényl}-1,3-thiazol-2-yl)carbamoyl]phényl}-2-méthylacrylique
(2E)-3-{2,6-Dichloro-4-[(4-{3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl}-1,3-thiazol-2-yl)carbamoyl]phenyl}-2-methylacrylic acid
2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)-
(2E)-3-{2,6-Dichlor-4-[(4-{3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl}-1,3-thiazol-2-yl)carbamoyl]phenyl}-2-methylacrylsäure
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