Phe-Lys(Trt)-PAB

Modify Date: 2025-09-10 15:28:56

Phe-Lys(Trt)-PAB Structure
Phe-Lys(Trt)-PAB structure
Common Name Phe-Lys(Trt)-PAB
CAS Number 1116085-99-4 Molecular Weight 640.81
Density 1.195±0.06 g/cm3(Predicted) Boiling Point 880.5±65.0 °C(Predicted)
Molecular Formula C41H44N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Phe-Lys(Trt)-PAB


Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].

 Names

Name Phe-Lys(Trt)-PAB

 Phe-Lys(Trt)-PAB Biological Activity

Description Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

References

[1]. Abu Ajaj K, et al. Development of protein-binding bifunctional linkers for a new generation of dual-actingprodrugs. Bioconjug Chem. 2009 Feb;20(2):390-6.

 Chemical & Physical Properties

Density 1.195±0.06 g/cm3(Predicted)
Boiling Point 880.5±65.0 °C(Predicted)
Molecular Formula C41H44N4O3
Molecular Weight 640.81
InChIKey SWCZCKQSLIJFDP-UWXQCODUSA-N
SMILES NC(=O)C(CCCCNC(c1ccccc1)(c1ccccc1)c1ccccc1)N(C(=O)C(N)Cc1ccccc1)c1ccc(CO)cc1
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