4-Dimethylaminopyridine

Modify Date: 2026-06-30 01:26:41

4-Dimethylaminopyridine Structure
4-Dimethylaminopyridine structure
Common Name 4-Dimethylaminopyridine
CAS Number 1122-58-3 Molecular Weight 122.17
Density 1.0±0.1 g/cm3 Boiling Point 162 ºC (50 mmHg)
Molecular Formula C7H10N2 Melting Point 108-113 ºC
MSDS Chinese USA Flash Point 110 ºC
Symbol GHS06
GHS06
Signal Word Danger

 Use of 4-Dimethylaminopyridine


N-(4-pyridyl)dimethylamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 4-Dimethylaminopyridine
Synonym More Synonyms

 4-Dimethylaminopyridine Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description N-(4-pyridyl)dimethylamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.0±0.1 g/cm3
Boiling Point 162 ºC (50 mmHg)
Melting Point 108-113 ºC
Molecular Formula C7H10N2
Molecular Weight 122.17
Flash Point 110 ºC
Exact Mass 122.084396
PSA 16.13000
LogP 1.34
Vapour Pressure 0.4±0.4 mmHg at 25°C
Index of Refraction 1.554
InChIKey VHYFNPMBLIVWCW-UHFFFAOYSA-N
SMILES CN(C)c1ccncc1
Storage condition Store in dark!
Stability Stable. Incompatible with acids, oxidizing agents.
Water Solubility 76 g/L (25 ºC)

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US9230000
CHEMICAL NAME :
Pyridine, 4-(dimethylamino)-
CAS REGISTRY NUMBER :
1122-58-3
BEILSTEIN REFERENCE NO. :
0110354
LAST UPDATED :
199710
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C7-H10-N2
MOLECULAR WEIGHT :
122.19
WISWESSER LINE NOTATION :
T6NJ DN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536502
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
470 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 14,111,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04228
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
13 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536502

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H310-H315-H319-H335
Precautionary Statements Missing Phrase - N15.00950417-P262-P280-P302 + P352 + P310-P305 + P351 + P338-P361 + P364
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T:Toxic
Risk Phrases R24/25;R34
Safety Phrases S36/37/39-S45-S28A-S26-S28-S36/37-S53-S27-S22
RIDADR UN 2811 6.1/PG 2
WGK Germany 3
RTECS US8400000
Packaging Group II
Hazard Class 8
HS Code 2933399090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles178

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Injectable Peptide Decorated Functional Nanofibrous Hollow Microspheres to Direct Stem Cell Differentiation and Tissue Regeneration.

Adv. Funct. Mater. 25(3) , 350-360, (2015)

Injectable microspheres are attractive stem cell carriers for minimally invasive procedures. For tissue regeneration, the microspheres need to present the critical cues to properly direct stem cell di...

Xerogel-sequestered silanated organochalcogenide catalysts for bromination with hydrogen peroxide and sodium bromide.

Molecules 20 , 9616-39, (2015)

While H2O2 is a powerful oxidant, decomposing into environmentally benign H2O and O2, a catalyst is often required for reactions with H2O2 to proceed at synthetically useful rates. Organotellurium and...

Remarkably regioselective deacylation of cellulose esters using tetraalkylammonium salts of the strongly basic hydroxide ion.

Carbohydr. Polym. 111 , 25-32, (2014)

Tetraalkylammonium hydroxides have been found to mediate regioselective deacylation of cellulose esters. This deacylation surprisingly shows substantial selectivity for the removal of the acyl groups ...

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

4-Dimethylaminopyrid
N4,N4-dimethylpyridin-4-amine
N-(4-Pyridyl)dimethylamine
4-dimethylamino pyridine
26DCLPY
4-Dimethylaminopyridine
N,N-dimethylpyridin-4-amine
5-22-09-00112 (Beilstein Handbook Reference)
MFCD00006244
DMAP
DMAP solution
N,N-Dimethyl-4-pyridinamine
p-dimethylaminopyridine
EINECS 214-353-5
4-Dimethylami
dimethylaminopyridine
AURORA KA-6495
4-Dimethylaminepyridine
4-(dimethylamino)pyridine
4-(Dimethylamino)pyridine,N,N-Dimethylpyridin-4-amine,DMAP
4-(N,N-dimethylamino)pyridine
UNII-PFP1R6P0S8
N,N-Dimethylpyridin-4-amine DMAP

 4-Dimethylaminopyridine | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: How is the water solubility of 4-Dimethylaminopyridine?
A: Water solubility of 4-Dimethylaminopyridine: 76 g/L (25 ºC).
Q: What is the LogP of 4-Dimethylaminopyridine?
A: LogP of 4-Dimethylaminopyridine is 1.34.
Q: What is the boiling point of 4-Dimethylaminopyridine?
A: Boiling point of 4-Dimethylaminopyridine is 162 ºC (50 mmHg).
Q: What is the InChIKey of 4-Dimethylaminopyridine?
A: InChIKey of 4-Dimethylaminopyridine is VHYFNPMBLIVWCW-UHFFFAOYSA-N.
Q: What is the molecular formula of 4-Dimethylaminopyridine?
A: Molecular formula of 4-Dimethylaminopyridine is C7H10N2.
Q: What is the safety information for 4-Dimethylaminopyridine?
A: Safety information for 4-Dimethylaminopyridine: S36/37/39-S45-S28A-S26-S28-S36/37-S53-S27-S22.
Q: What is the CAS number of 4-Dimethylaminopyridine?
A: CAS number of 4-Dimethylaminopyridine is 1122-58-3.
Q: What are the uses of 4-Dimethylaminopyridine?
A: Main uses of 4-Dimethylaminopyridine: N-(4-pyridyl)dimethylamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Q: What is the melting point of 4-Dimethylaminopyridine?
A: Melting point of 4-Dimethylaminopyridine is 108-113 ºC.
Q: What are the downstream products of 4-Dimethylaminopyridine?
A: Related downstream products(CAS) of 4-Dimethylaminopyridine: 111055-14-2;110465-52-6;396092-82-3;55447-00-2;5093-64-1;4214-57-7;90345-66-7;4663-97-2;1801-10-1;50533-97-6.

 4-Dimethylaminopyridinefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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