L-Gulonic g-lactone

Modify Date: 2024-01-02 19:04:49

L-Gulonic g-lactone Structure
L-Gulonic g-lactone structure
Common Name L-Gulonic g-lactone
CAS Number 1128-23-0 Molecular Weight 178.140
Density 1.8±0.1 g/cm3 Boiling Point 467.9±18.0 °C at 760 mmHg
Molecular Formula C6H10O6 Melting Point 187-190ºC(lit.)
MSDS N/A Flash Point 201.5±14.7 °C

 Use of L-Gulonic g-lactone


L-Gulono-1,4-lactone is a substrate of L-gulono-1,4-lactone oxidoreductase, which catalyzes the last step of the biosynthesis of L-ascorbic (Vatamin) C. In other words, L-Gulono-1,4-lactone is a direct precursor of vitamin C in animals, in plants and in some protists.

 Names

Name L-gulono-1,4-lactone
Synonym More Synonyms

 L-Gulonic g-lactone Biological Activity

Description L-Gulono-1,4-lactone is a substrate of L-gulono-1,4-lactone oxidoreductase, which catalyzes the last step of the biosynthesis of L-ascorbic (Vatamin) C. In other words, L-Gulono-1,4-lactone is a direct precursor of vitamin C in animals, in plants and in some protists.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Wolucka BA, et al. Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L-gulono-1,4-lactone dehydrogenase. FEBS J. 2006 Oct;273(19):4435-45. Epub 2006 Sep 5.

 Chemical & Physical Properties

Density 1.8±0.1 g/cm3
Boiling Point 467.9±18.0 °C at 760 mmHg
Melting Point 187-190ºC(lit.)
Molecular Formula C6H10O6
Molecular Weight 178.140
Flash Point 201.5±14.7 °C
Exact Mass 178.047745
PSA 107.22000
LogP -3.15
Vapour Pressure 0.0±2.6 mmHg at 25°C
Index of Refraction 1.625
Storage condition 2~8°C

 Safety Information

Hazard Codes Xi
Safety Phrases 22-24/25
WGK Germany 3
HS Code 2932209090

 Synthetic Route

~96%

L-Gulonic g-lactone Structure

L-Gulonic g-lactone

CAS#:1128-23-0

Literature: Andrews; Crawford; Bacon Journal of Organic Chemistry, 1981 , vol. 46, # 14 p. 2976 - 2977

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L-Gulonic g-lactone Structure

L-Gulonic g-lactone

CAS#:1128-23-0

Literature: Journal of the American Chemical Society, , vol. 67, p. 1713 Recueil des Travaux Chimiques des Pays-Bas, , vol. 74, p. 1365,1367

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L-Gulonic g-lactone Structure

L-Gulonic g-lactone

CAS#:1128-23-0

Literature: Synlett, , # 8 p. 1247 - 1250

~%

L-Gulonic g-lactone Structure

L-Gulonic g-lactone

CAS#:1128-23-0

Literature: Synlett, , # 8 p. 1247 - 1250

~%

L-Gulonic g-lactone Structure

L-Gulonic g-lactone

CAS#:1128-23-0

Literature: Helvetica Chimica Acta, , vol. 21, p. 1210,1216

~%

L-Gulonic g-lactone Structure

L-Gulonic g-lactone

CAS#:1128-23-0

Literature: Helvetica Chimica Acta, , vol. 21, p. 1210,1216

 Customs

HS Code 2932209090
Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

L-(+)-Gulonic Acid gaMMa-Lactone
L-Gulonic g-lactone
L-(+)-Gulonic Acid γ-Lactone
MFCD00064331
L-Gulonic acid γ-lactone
(3S,4R,5R)-5-((S)-1,2-Dihydroxyethyl)-3,4-dihydroxydihydrofuran-2(3H)-one
(3S,4R,5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-one
L-Gulonolactone
(3S,4R,5R)-5-[(1S)-1,2-Dihydroxyethyl]-3,4-dihydroxydihydrofuran-2(3H)-on (non-preferred name)
(3S,4R,5R)-5-[(1S)-1,2-Dihydroxyethyl]-3,4-dihydroxydihydrofuran-2(3H)-one (non-preferred name)
L-gulono-1,4-lactone
(3S,4R,5R)-5-[(1S)-1,2-Dihydroxyethyl]-3,4-dihydroxydihydro-2(3H)-furanone
L(+)-Gulonic acid gamma-lactone