3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXIMIDAMIDE
3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXIMIDAMIDE structure
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Common Name | 3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXIMIDAMIDE | ||
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| CAS Number | 1131-64-2 | Molecular Weight | 175.23 | |
| Density | 1.24g/cm3 | Boiling Point | 309.8ºC at 760mmHg | |
| Molecular Formula | C10H13N3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 141.1ºC | |
Use of 3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXIMIDAMIDEDebrisoquin (Isocaramidine) is a TMPRSS2 inhibitors that inhibits SARS-CoV-2 entry into human lung cell line by a TMPRSS2-depedent manner, with an IC50 of 22μM. Debrisoquin can be used for antiviral research[1]. |
Summary: Debrisoquin, also known as 3,4-Dihydroisoquinoline-2(1H)-carboximidamide, has a CAS number of 1131-64-2. Its molecular formula is C10H13N3 and molecular weight is 175.23. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | debrisoquin |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Debrisoquin (Isocaramidine) is a TMPRSS2 inhibitors that inhibits SARS-CoV-2 entry into human lung cell line by a TMPRSS2-depedent manner, with an IC50 of 22μM. Debrisoquin can be used for antiviral research[1]. |
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| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.24g/cm3 |
|---|---|
| Boiling Point | 309.8ºC at 760mmHg |
| Molecular Formula | C10H13N3 |
| Molecular Weight | 175.23 |
| Flash Point | 141.1ºC |
| Exact Mass | 175.11100 |
| PSA | 53.11000 |
| LogP | 1.67610 |
| Vapour Pressure | 0.000626mmHg at 25°C |
| Index of Refraction | 1.649 |
| InChIKey | JWPGJSVJDAJRLW-UHFFFAOYSA-N |
| SMILES | N=C(N)N1CCc2ccccc2C1 |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| HS Code | 2933499090 |
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This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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3,4-DIHYDROISOQ... CAS#:1131-64-2 |
| Literature: Gruenewald, Sanja; Wahl, Bettina; Bittner, Florian; Hungeling, Helen; Kanzow, Stephanie; Kotthaus, Joscha; Schwering, Ulrike; Mendel, Ralf R.; Clement, Bernd Journal of Medicinal Chemistry, 2008 , vol. 51, # 24 p. 8173 - 8177 |
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3,4-DIHYDROISOQ... CAS#:1131-64-2 |
| Literature: McNeilab, Inc. Patent: US4656291 A1, 1987 ; |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 2 | |
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| DownStream 1 | |
CAS#:59333-79-8This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933499090 |
|---|---|
| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 3,4-Dihydroisoquinoline-2(1H)-carboxiMidaMide |
| EINECS 214-470-1 |
| 3,4-Dihydro-2(1H)-isochinolin-carboxamidin |
| 3,4-dihydro-1H-isoquinoline-2-carboximidic acid amide |
| 3,4-Dihydro-2(1H)-isoquinolinecarboximidamide |
| Debrisoquin |
| Debrisochin |
| 1,2,3,4-Tetrahydroisochinolin-N-carboxamidin |
| 3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXAMIDINE |
| Isocaramidine |
| 3,4-Dihydro-2(1H)-isoquinolinecarbimidamide |
| 3,4-dihydro-1H-isoquinoline-2-carboximidamide |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What English synonyms does debrisoquin have? |
| A: English synonyms of debrisoquin: 3,4-Dihydroisoquinoline-2(1H)-carboxiMidaMide, EINECS 214-470-1, 3,4-Dihydro-2(1H)-isochinolin-carboxamidin, 3,4-dihydro-1H-isoquinoline-2-carboximidic acid amide, 3,4-Dihydro-2(1H)-isoquinolinecarboximidamide, Debrisoquin, Debrisochin, 1,2,3,4-Tetrahydroisochinolin-N-carboxamidin, 3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXAMIDINE, Isocaramidine, 3,4-Dihydro-2(1H)-isoquinolinecarbimidamide, 3,4-dihydro-1H-isoquinoline-2-carboximidamide. |
| Q: What is the LogP of debrisoquin? |
| A: LogP of debrisoquin is 1.67610. |
| Q: What is the polar surface area (PSA) of debrisoquin? |
| A: Polar surface area (PSA) of debrisoquin is 53.11000. |
| Q: What is the English name of debrisoquin? |
| A: The English name of debrisoquin is debrisoquin. |
| Q: What are the uses of debrisoquin? |
| A: Main uses of debrisoquin: Debrisoquin (Isocaramidine) is a TMPRSS2 inhibitors that inhibits SARS-CoV-2 entry into human lung cell line by a TMPRSS2-depedent manner, with an IC50 of 22μM. Debrisoquin can be used for antiviral research[1]. |
| Q: What are the downstream products of debrisoquin? |
| A: Related downstream products(CAS) of debrisoquin: 59333-79-8. |
| Q: What is the InChIKey of debrisoquin? |
| A: InChIKey of debrisoquin is JWPGJSVJDAJRLW-UHFFFAOYSA-N. |
| Q: What are the upstream materials of debrisoquin? |
| A: Related upstream materials(CAS) of debrisoquin: 91-21-4;1184-90-3. |
| Q: What is the CAS number of debrisoquin? |
| A: CAS number of debrisoquin is 1131-64-2. |
| Q: What is the SMILES notation of debrisoquin? |
| A: SMILES notation of debrisoquin is N=C(N)N1CCc2ccccc2C1. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Dayang Chem (Hangzhou) Co., Ltd. |