Fosamprenavir-d4

Modify Date: 2024-01-13 17:48:32

Fosamprenavir-d4 structure	Common Name	Fosamprenavir-d4
	CAS Number	1133702-41-6	Molecular Weight	589.63
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₃₂D₄N₃O₉PS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Fosamprenavir-d4

Fosamprenavir-d4 is deuterium labeled Fosamprenavir. Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility[1]. Anti-HIV infection[1].

Name	Fosamprenavir-d4

Description	Fosamprenavir-d4 is deuterium labeled Fosamprenavir. Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility[1]. Anti-HIV infection[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Falcoz C, et al. Pharmacokinetics of GW433908, a prodrug of amprenavir, in healthy male volunteers. J Clin Pharmacol. 2002 Aug;42(8):887-98.

Molecular Formula	C₂₅H₃₂D₄N₃O₉PS
Molecular Weight	589.63

Fosamprenavir-d4

Use of Fosamprenavir-d4

Names

Fosamprenavir-d4 Biological Activity

Chemical & Physical Properties