Pedunculagin
Modify Date: 2025-09-18 14:35:37
Pedunculagin structure
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Common Name | Pedunculagin | ||
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| CAS Number | 113866-64-1 | Molecular Weight | 784.54100 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C34H24O22 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PedunculaginPedunculagin is a potent 5α-reductase type 1 inhibitor. Pedunculagin inhibits nitric oxide (NO), IL-6, IL-8 production. Pedunculagin decreases the protein expression of 5α-reductase. Pedunculagin shows anti-inflammatory activity[1]. |
| Name | Pedunculagin |
|---|---|
| Synonym | More Synonyms |
| Description | Pedunculagin is a potent 5α-reductase type 1 inhibitor. Pedunculagin inhibits nitric oxide (NO), IL-6, IL-8 production. Pedunculagin decreases the protein expression of 5α-reductase. Pedunculagin shows anti-inflammatory activity[1]. |
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| Related Catalog | |
| In Vitro | Pedunculagin 在 RAW 246.7 细胞 中抑制一氧化氮 (NO) 的产生，IC50 值为 53.52 µM[1]。 Pedunculagin 在 HaCaT 细胞中抑制 IL-6、IL-8 的产生，IC50 分别为 6.59、0.09 µM[1]。 Pedunculagin (25, 50, 100 µM; 24 h) 降低 HaCaT 细胞中 5α-还原酶的蛋白表达[1]。 Western Blot Analysis[1] Cell Line: HaCaT cells Concentration: 25, 50, 100 µM Incubation Time: 24 h Result: Decreased the 5α-reductase protein expression in a dose-dependent manner. |
| References |
| Molecular Formula | C34H24O22 |
|---|---|
| Molecular Weight | 784.54100 |
| Exact Mass | 784.07600 |
| PSA | 377.42000 |
| LogP | 0.66540 |
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| .pedunculagin |