Pedunculagin

Modify Date: 2024-01-08 18:37:44

Pedunculagin Structure
Pedunculagin structure
 Common Name Pedunculagin
CAS Number 113866-64-1 Molecular Weight 784.54100
Density N/A Boiling Point N/A
Molecular Formula C34H24O22 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pedunculagin


Pedunculagin is a potent 5α-reductase type 1 inhibitor. Pedunculagin inhibits nitric oxide (NO), IL-6, IL-8 production. Pedunculagin decreases the protein expression of 5α-reductase. Pedunculagin shows anti-inflammatory activity[1].

 Names

Name Pedunculagin
Synonym More Synonyms

 Pedunculagin Biological Activity

Description Pedunculagin is a potent 5α-reductase type 1 inhibitor. Pedunculagin inhibits nitric oxide (NO), IL-6, IL-8 production. Pedunculagin decreases the protein expression of 5α-reductase. Pedunculagin shows anti-inflammatory activity[1].
Related Catalog
In Vitro Pedunculagin 在 RAW 246.7 细胞 中抑制一氧化氮 (NO) 的产生，IC50 值为 53.52 µM[1]。 Pedunculagin 在 HaCaT 细胞中抑制 IL-6、IL-8 的产生，IC50 分别为 6.59、0.09 µM[1]。 Pedunculagin (25, 50, 100 µM; 24 h) 降低 HaCaT 细胞中 5α-还原酶的蛋白表达[1]。 Western Blot Analysis[1] Cell Line: HaCaT cells Concentration: 25, 50, 100 µM Incubation Time: 24 h Result: Decreased the 5α-reductase protein expression in a dose-dependent manner.
References

[1]. Kim M, et al. Anti-Acne Vulgaris Effects of Pedunculagin from the Leaves of Quercus mongolica by Anti-Inflammatory Activity and 5α-Reductase Inhibition. Molecules. 2020 May 5;25(9):2154.  

 Chemical & Physical Properties

Molecular Formula C34H24O22
Molecular Weight 784.54100
Exact Mass 784.07600
PSA 377.42000
LogP 0.66540

 Synonyms

2,3,4,6-bis-(S)-HHDP-D-glucose
.pedunculagin
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Chemsrc provides Pedunculagin(CAS#:113866-64-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Pedunculagin are included as well.>> amp version: Pedunculagin

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