Calcineurin Substrate trifluoroacetate salt structure
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Common Name | Calcineurin Substrate trifluoroacetate salt | ||
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CAS Number | 113873-67-9 | Molecular Weight | 2112.35000 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C92H150N28O29 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | N/A |
Use of Calcineurin Substrate trifluoroacetate saltCalcineurin substrate is a peptide from the regulatory RII subunit of cAMP-dependent protein kinase. It can be used in the calcineurin activity assay. |
Name | Calcineurin substrate |
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Synonym | More Synonyms |
Description | Calcineurin substrate is a peptide from the regulatory RII subunit of cAMP-dependent protein kinase. It can be used in the calcineurin activity assay. |
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Related Catalog | |
In Vitro | Calcineurin (PP2B), a serine/threonine phosphatase controlled by cellular calcium, has been implicated in a wide variety of biological responses including lymphocyte activation, neuronal and muscle development, neurite outgrowth, and morphogenesis of vertebrate heart valves[1]. |
References |
Molecular Formula | C92H150N28O29 |
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Molecular Weight | 2112.35000 |
Exact Mass | 2111.11000 |
PSA | 924.67000 |
LogP | 1.58550 |
Storage condition | −20°C |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
Endoplasmic reticulum vacuolation and unfolded protein response leading to paraptosis like cell death in cyclosporine A treated cancer cervix cells is mediated by cyclophilin B inhibition.
Biochim. Biophys. Acta 1843(11) , 2497-512, (2014) Cyclosporine A (CsA), a widely used immunosuppressant shows cytotoxic effects by either inducing apoptosis or redirecting the cell towards non-apoptotic cell death. However, there still remains a lacu... |
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Myocyte enhancer factor (MEF)-2 plays essential roles in T-cell transformation associated with HTLV-1 infection by stabilizing complex between Tax and CREB.
Retrovirology 12 , 23, (2015) The exact molecular mechanisms regarding HTLV-1 Tax-mediated viral gene expression and CD4 T-cell transformation have yet to be fully delineated. Herein, utilizing virus-infected primary CD4+ T cells ... |
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Nonradioactive assay for protein phosphatase 2B (calcineurin) activity using a partial sequence of the subunit of cAMP-dependent protein kinase as substrate.
Anal. Biochem. 216 , 147, (1994) Currently, protein phosphatase 2B (calcineurin) activity is assayed based on release of [32P]phosphate from a 19-amino acid peptide (partial sequence of the regulatory subunit of cAMP-dependent protei... |
MFCD00236901 |
DLDVPIPGRFDRRVSVAAE |