Calcineurin Substrate trifluoroacetate salt

Modify Date: 2024-01-02 13:40:17

Calcineurin Substrate trifluoroacetate salt Structure
Calcineurin Substrate trifluoroacetate salt structure
Common Name Calcineurin Substrate trifluoroacetate salt
CAS Number 113873-67-9 Molecular Weight 2112.35000
Density N/A Boiling Point N/A
Molecular Formula C92H150N28O29 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of Calcineurin Substrate trifluoroacetate salt


Calcineurin substrate is a peptide from the regulatory RII subunit of cAMP-dependent protein kinase. It can be used in the calcineurin activity assay.

 Names

Name Calcineurin substrate
Synonym More Synonyms

  Biological Activity

Description Calcineurin substrate is a peptide from the regulatory RII subunit of cAMP-dependent protein kinase. It can be used in the calcineurin activity assay.
Related Catalog
In Vitro Calcineurin (PP2B), a serine/threonine phosphatase controlled by cellular calcium, has been implicated in a wide variety of biological responses including lymphocyte activation, neuronal and muscle development, neurite outgrowth, and morphogenesis of vertebrate heart valves[1].
References

[1]. Crabtree GR, et al. Calcium, calcineurin, and the control of transcription. J Biol Chem. 2001 Jan 26;276(4):2313-6.

 Chemical & Physical Properties

Molecular Formula C92H150N28O29
Molecular Weight 2112.35000
Exact Mass 2111.11000
PSA 924.67000
LogP 1.58550
Storage condition −20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles3

More Articles
Endoplasmic reticulum vacuolation and unfolded protein response leading to paraptosis like cell death in cyclosporine A treated cancer cervix cells is mediated by cyclophilin B inhibition.

Biochim. Biophys. Acta 1843(11) , 2497-512, (2014)

Cyclosporine A (CsA), a widely used immunosuppressant shows cytotoxic effects by either inducing apoptosis or redirecting the cell towards non-apoptotic cell death. However, there still remains a lacu...

Myocyte enhancer factor (MEF)-2 plays essential roles in T-cell transformation associated with HTLV-1 infection by stabilizing complex between Tax and CREB.

Retrovirology 12 , 23, (2015)

The exact molecular mechanisms regarding HTLV-1 Tax-mediated viral gene expression and CD4 T-cell transformation have yet to be fully delineated. Herein, utilizing virus-infected primary CD4+ T cells ...

Nonradioactive assay for protein phosphatase 2B (calcineurin) activity using a partial sequence of the subunit of cAMP-dependent protein kinase as substrate.

Anal. Biochem. 216 , 147, (1994)

Currently, protein phosphatase 2B (calcineurin) activity is assayed based on release of [32P]phosphate from a 19-amino acid peptide (partial sequence of the regulatory subunit of cAMP-dependent protei...

 Synonyms

MFCD00236901
DLDVPIPGRFDRRVSVAAE