Aminohexylgeldanamycin hydrochloride

Modify Date: 2025-08-27 17:19:21

Aminohexylgeldanamycin hydrochloride Structure
Aminohexylgeldanamycin hydrochloride structure
Common Name Aminohexylgeldanamycin hydrochloride
CAS Number 1146534-45-3 Molecular Weight 681.26
Density N/A Boiling Point N/A
Molecular Formula C34H53ClN4O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Aminohexylgeldanamycin hydrochloride


Aminohexylgeldanamycin (AHGDM) hydrochloride, a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin hydrochloride shows antiangiogenic and antitumor activities[1].

 Names

Name Aminohexylgeldanamycin hydrochloride

 Aminohexylgeldanamycin hydrochloride Biological Activity

Description Aminohexylgeldanamycin (AHGDM) hydrochloride, a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin hydrochloride shows antiangiogenic and antitumor activities[1].
Related Catalog
Target

HSP90

In Vitro HPMA copolymer-aminohexylgeldanamycin conjugates target cell surface expressed GRP78 in prostate cancer[2].
References

[1]. Greish K, et al. Anticancer and antiangiogenic activity of HPMA copolymer-aminohexylgeldanamycin-RGDfK conjugates for prostate cancer therapy. J Control Release. 2011;151(3):263-270.

[2]. Larson N, et al. HPMA copolymer-aminohexylgeldanamycin conjugates targeting cell surface expressed GRP78 in prostate cancer. Pharm Res. 2010;27(12):2683-2693.

 Chemical & Physical Properties

Molecular Formula C34H53ClN4O8
Molecular Weight 681.26
InChIKey KIDYRDGTJBAQHJ-CZSHERGUSA-N
SMILES COC1C=CC=C(C)C(=O)NC2=CC(=O)C(NCCCCCCN)=C(CC(C)CC(OC)C(O)C(C)C=C(C)C1OC(N)=O)C2=O.Cl
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.