arg-pro-pro-gly-phe-ser-pro-leu acetate salt
arg-pro-pro-gly-phe-ser-pro-leu acetate salt structure
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Common Name | arg-pro-pro-gly-phe-ser-pro-leu acetate salt | ||
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| CAS Number | 115035-45-5 | Molecular Weight | 930.06 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C43H67N11O12 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of arg-pro-pro-gly-phe-ser-pro-leu acetate saltDes-Arg9-[Leu8]-Bradykinin acetate is potent bradykinin receptor 1 (B1R) antagonist. Des-Arg9-[Leu8]-Bradykinin acetate can be used for renal fibrosis research[1]. |
| Name | arg-pro-pro-gly-phe-ser-pro-leu acetate salt |
|---|---|
| Synonym | More Synonyms |
| Description | Des-Arg9-[Leu8]-Bradykinin acetate is potent bradykinin receptor 1 (B1R) antagonist. Des-Arg9-[Leu8]-Bradykinin acetate can be used for renal fibrosis research[1]. |
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| Related Catalog | |
| Target |
IC50: B1R[1] |
| References |
| Molecular Formula | C43H67N11O12 |
|---|---|
| Molecular Weight | 930.06 |
| Exact Mass | 929.49700 |
| PSA | 360.08000 |
| LogP | 0.84570 |
| InChIKey | XBFMNOKHQZCARQ-XXZMQFNDSA-N |
| SMILES | CC(=O)O.CC(C)CC(NC(=O)C1CCCN1C(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C1CCCN1C(=O)C1CCCN1C(=O)C(N)CCCN=C(N)N)C(=O)O |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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Upregulation of B1 receptor mediating des-Arg9-BK-induced rat paw oedema by systemic treatment with bacterial endotoxin.
Br. J. Pharmacol. 117 , 793-798, (1996) 1. The effect of pretreatment with bacterial endotoxin (LPS, 10 micrograms, i.v., 24 h) on the bradykinin B1 and B2 receptor-induced oedema in the rat paw, and the interaction of B1-mediated responses... |
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Angiotensin II type 2 receptor expression after vascular injury: differing effects of angiotensin-converting enzyme inhibition and angiotensin receptor blockade.
Hypertension 48 , 942-949, (2006) It has been suggested that the effects of angiotensin II type 1 receptor (AT1R) blockers are in part because of angiotensin II type 2 receptor (AT2R) signaling. Interactions between the AT2R and kinin... |
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The role of kinin B1 receptors in the nociception produced by peripheral protein kinase C activation in mice.
Neuropharmacology 54 , 597-604, (2008) The peripheral injection of phorbol myristate acetate (PMA) into the mouse paw induces nociception mediated through activation of protein kinase C (PKC). In the present study, we examine the contribut... |
| arg-pro-pro-gly-phe-ser-pro-leu acoh 3h2o |