SR 13800

Modify Date: 2025-08-27 19:33:22

SR 13800 structure	Common Name	SR 13800
	CAS Number	227321-12-2	Molecular Weight	435.58
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₉N₃O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SR 13800

MCT1-IN-2 is a potent monocarboxylate transporter 1 (MCT1) inhibitor. MCT1-IN-2 has anti-cancer activity[1][2].

Name	MCT1-IN-2

Description	MCT1-IN-2 is a potent monocarboxylate transporter 1 (MCT1) inhibitor. MCT1-IN-2 has anti-cancer activity[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Monocarboxylate Transporter Research Areas >> Cancer
In Vitro	MCT1-IN-2 (compound 3) has a pKi of 9.48 for Jurkat T-cells and inhibits human peripheral blood mononuclear cells (PBMC) proliferation (pIC50=8.61)[1]. MCT1-IN-2 (compound 1) has an EC50 of 5.5 nM (MTT assay) and an IC50 of 105 nM (lactate transport inhibition assay) in human Raji lymphoma cell proliferation[2].
References	[1]. Clare M Murray, et al. Monocarboxylate transporter MCT1 is a target for immunosuppression. Nat Chem Biol. 2005 Dec;1(7):371-6. [2]. Hui Wang, et al. Synthesis and structure-activity relationships of pteridine dione and trione monocarboxylate transporter 1 inhibitors. J Med Chem. 2014 Sep 11;57(17):7317-24.

Molecular Formula	C₂₅H₂₉N₃O₂S
Molecular Weight	435.58

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: SR 13800
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: MCT1-IN-2
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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