Benzyl salicylate

Modify Date: 2024-01-02 14:29:39

Benzyl salicylate Structure
Benzyl salicylate structure
Common Name Benzyl salicylate
CAS Number 118-58-1 Molecular Weight 228.243
Density 1.2±0.1 g/cm3 Boiling Point 320.0±0.0 °C at 760 mmHg
Molecular Formula C14H12O3 Melting Point 18-20 °C
MSDS Chinese USA Flash Point 146.4±13.7 °C
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning

 Use of Benzyl salicylate


Benzyl salicylate is a salicylic acid benzyl ester. It can be used as a fragrance additive or UV light absorber.

 Names

Name Benzyl salicylate
Synonym More Synonyms

 Benzyl salicylate Biological Activity

Description Benzyl salicylate is a salicylic acid benzyl ester. It can be used as a fragrance additive or UV light absorber.
Related Catalog
References

[1]. María A Pastor-Nieto, et al. Sensitization to benzyl salicylate and other allergens in patients with frontal fibrosing alopecia. Contact Dermatitis. 2021 Jun;84(6):423-430.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 320.0±0.0 °C at 760 mmHg
Melting Point 18-20 °C
Molecular Formula C14H12O3
Molecular Weight 228.243
Flash Point 146.4±13.7 °C
Exact Mass 228.078644
PSA 46.53000
LogP 4.01
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.607
Water Solubility Slightly soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VO1750000
CHEMICAL NAME :
Salicylic acid, benzyl ester
CAS REGISTRY NUMBER :
118-58-1
BEILSTEIN REFERENCE NO. :
2115365
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C14-H12-O3
MOLECULAR WEIGHT :
228.26
WISWESSER LINE NOTATION :
QR BVO1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2227 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 11,1029,1973 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82924 No. of Facilities: 71 (estimated) No. of Industries: 4 No. of Occupations: 25 No. of Employees: 6137 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82924 No. of Facilities: 5081 (estimated) No. of Industries: 20 No. of Occupations: 46 No. of Employees: 74153 (estimated) No. of Female Employees: 42575 (estimated)

 Safety Information

Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning
Hazard Statements H317-H319-H371
Precautionary Statements P260-P280-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36-S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS VO1750000
HS Code 2918230000

 Synthetic Route

 Customs

HS Code 2918230000
Summary 2918230000 other esters of salicylic acid and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles14

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Atmospheric pressure gas chromatography-time-of-flight-mass spectrometry (APGC-ToF-MS) for the determination of regulated and emerging contaminants in aqueous samples after stir bar sorptive extraction (SBSE).

Anal. Chim. Acta 851 , 1-13, (2014)

This work presents the development, optimization and validation of a multi-residue method for the simultaneous determination of 102 contaminants, including fragrances, UV filters, repellents, endocrin...

Optimization of an analytical methodology for the simultaneous determination of different classes of ultraviolet filters in cosmetics by pressurized liquid extraction-gas chromatography tandem mass spectrometry.

J. Chromatogr. A. 1405 , 12-22, (2015)

A methodology based on pressurized liquid extraction (PLE) followed by gas chromatography-tandem mass spectrometry (GC-MS/MS) has been developed for the simultaneous analysis of different classes of U...

Insulin sensitivity of liver glycogen synthase b into a conversion.

Mol. Cell Biochem. 25(1) , 47-59, (1979)

Liver glycogen synthase b phosphatase, chromatographically separable from phosphorylase a phosphatase, is decreased in 48-hour alloxan diabetic rats. The phosphatase activities are measured in an in v...

 Synonyms

benzyl 2-hydroxybenzoate
Salicylic Acid Benzyl Ester
Benzoic acid, 2-hydroxy-, phenylmethyl ester
2-Hydroxybenzoic Acid Benzyl Ester
2-Hydroxybenzoic acid, phenylmethyl ester
2-(HO)C6H4CO2CH2C6H5
Benzyl salicylate
Salicylic acid, benzyl ester
2-Hydroxybenzoic acid phenylmethyl ester
Benzyl o-hydroxybenzoate
phenylmethyl 2-hydroxybenzoate
EINECS 204-262-9
Salicyclic acid benzyl ester
MFCD00020034