Maltol

Modify Date: 2025-08-20 23:53:52

Maltol Structure
Maltol structure
 Common Name Maltol
CAS Number 118-71-8 Molecular Weight 126.110
Density 1.3±0.1 g/cm3 Boiling Point 284.7±40.0 °C at 760 mmHg
Molecular Formula C6H6O3 Melting Point 160-164 °C(lit.)
MSDS Chinese USA Flash Point 127.3±20.8 °C
Symbol GHS07
GHS07		 Signal Word Warning

 Use of Maltol


Maltol, a type of aromatic compound, exists in high concentrations in red ginseng. Maltol is a potent antioxidative agent and typically is used to enhance flavor and preserve food[1].

 Names

Name 3-Hydroxy-2-methyl-4H-pyran-4-one
Synonym More Synonyms

 Maltol Biological Activity

Description Maltol, a type of aromatic compound, exists in high concentrations in red ginseng. Maltol is a potent antioxidative agent and typically is used to enhance flavor and preserve food[1].
Related Catalog
References

[1]. Guo N, et al. Maltol, a food flavor enhancer, attenuates diabetic peripheral neuropathy in streptozotocin-induceddiabetic rats. Food Funct. 2018 Dec 13;9(12):6287-6297.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 284.7±40.0 °C at 760 mmHg
Melting Point 160-164 °C(lit.)
Molecular Formula C6H6O3
Molecular Weight 126.110
Flash Point 127.3±20.8 °C
Exact Mass 126.031693
PSA 50.44000
LogP 0.08
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.561
Water Solubility 1.2 g/100 mL (25 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ1050000
CHEMICAL NAME :
4H-Pyran-4-one, 3-hydroxy-2-methyl-
CAS REGISTRY NUMBER :
118-71-8
BEILSTEIN REFERENCE NO. :
0112169
LAST UPDATED :
199712
DATA ITEMS CITED :
17
MOLECULAR FORMULA :
C6-H6-O3
MOLECULAR WEIGHT :
126.12
WISWESSER LINE NOTATION :
T6O DVJ B1 CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1410 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
550 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD16 - Lethal Dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
820 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1620 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1410 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
3720 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
90 gm/kg/90D-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
20500 mg/kg/41D-I
TOXIC EFFECTS :
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 26,487,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2610 No. of Facilities: 508 (estimated) No. of Industries: 3 No. of Occupations: 5 No. of Employees: 1733 (estimated) No. of Female Employees: 642 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Precautionary Statements P301 + P312 + P330
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R22;R36/37/38
Safety Phrases S37-S37/39-S26-S36-S36/37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS UQ1050000
HS Code 2932999099

 Synthetic Route

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles34

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 Synonyms

3-Hydroxy-2-methyl-4H-pyran-4-one
MALTENE
3-hydroxy-2-methyl-4-pyrone
3-Hydroxy-2-methyl-g-pyrone
Vetol
Palatone
Laricin
4H-Pyran-4-one, 3-hydroxy-2-methyl-
Talmon
3-Hydroxy-2-methyl-4-pyrone,Maltol
2-methyl-3-hydroxy-4H-pyran-4-one
MALTOL FCC
Veltol
Maltol
2-methyl-3-oxy-4H-pyran-4-one
2-methyl-3-hydroxy-4-pyranone
EINECS 204-271-8
MFCD00006578
FEMA 2656
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Related Compounds: More...
Maltolate
103616-17-7
Ethyl maltol
4940-11-8
acetylmaltol
28787-36-2
Ferric maltol
33725-54-1
Maltol butyrate
67860-01-9
O-benzyl maltol
61049-69-2
Maltol Propionate
68555-63-5
Maltol isobutyrate
65416-14-0
ethyl maltol butyrate
93805-72-2
Methyl 1-(2-cyclopropoxyethyl)-1H-indazole-4-carboxylate
1431308-26-7
(1R,3R)-2,2-Dimethyl-3-pyridin-4-ylcyclopropane-1-carboxylic acid
2227725-59-7
rac-(1R,3R)-2,2-dimethyl-3-(pyridin-2-yl)cyclopropane-1-carboxylic acid
2227802-53-9
4-(3,5-Dichloro-4-pyridinyl)benzoic acid methyl ester
1456869-52-5
rac-(1R,3R)-2,2-dimethyl-3-(pyridin-3-yl)cyclopropane-1-carboxylic acid
2227914-68-1
Methyl 1-(2-(2-oxopyrrolidin-1-yl)ethyl)-1H-indole-4-carboxylate
1431307-98-0
Benzyl cyclopropyl(2-methoxy-5,6,7,8-tetrahydroquinazolin-6-yl)carbamate
1431308-35-8
Tert-butyl 4-(3-(4-nitrophenyl)propyl)piperazine-1-carboxylate
1432126-02-7
(2S)-5-(4-Methoxyphenyl)pentan-2-amine
2248184-04-3
(S)-7-Methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
190579-84-1
Chemsrc provides Maltol(CAS#:118-71-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Maltol are included as well.>> amp version: Maltol

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