EGFR/HER2/CDK9-IN-2

Modify Date: 2024-01-16 18:30:11

EGFR/HER2/CDK9-IN-2 structure	Common Name	EGFR/HER2/CDK9-IN-2
	CAS Number	1180924-34-8	Molecular Weight	496.56
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₀N₄O₅S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of EGFR/HER2/CDK9-IN-2

EGFR/HER2/CDK9-IN-2 (Compound 9) is a potent inhibitor of EGFR/HER2/CDK9 with IC50s of 145.35, 129.07, and 117.13 nM, respectively. EGFR/HER2/CDK9-IN-2 exhibits remarkable antitumor activity[1].

Name	EGFR/HER2/CDK9-IN-2

Description	EGFR/HER2/CDK9-IN-2 (Compound 9) is a potent inhibitor of EGFR/HER2/CDK9 with IC50s of 145.35, 129.07, and 117.13 nM, respectively. EGFR/HER2/CDK9-IN-2 exhibits remarkable antitumor activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
References	[1]. El-Azab AS, et al. Antitumor activity, multitarget mechanisms, and molecular docking studies of quinazoline derivatives based on a benzenesulfonamide scaffold: Cell cycle analysis. Bioorg Chem. 2020;104:104345.

Molecular Formula	C₂₃H₂₀N₄O₅S₂
Molecular Weight	496.56