AF-DX 384

Modify Date: 2024-01-04 09:31:32

AF-DX 384 structure	Common Name	AF-DX 384
	CAS Number	118290-26-9	Molecular Weight	478.630
	Density	1.1±0.1 g/cm3	Boiling Point	618.4±55.0 °C at 760 mmHg
	Molecular Formula	C₂₇H₃₈N₆O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	327.8±31.5 °C

Use of AF-DX 384

AF-DX 384 is a selective antagonist of M2 and M4 muscarinic acetylcholine receptors (Kis=6.03 and 10 nM, respectively)[1]. AF-DX 384 reverses deficits in novel object recognition and passive avoidance in aged rats, as well as in young rats with impairments induced by scopolamine[2].

Name	AFDX384
Synonym	More Synonyms

Description	AF-DX 384 is a selective antagonist of M2 and M4 muscarinic acetylcholine receptors (Kis=6.03 and 10 nM, respectively)[1]. AF-DX 384 reverses deficits in novel object recognition and passive avoidance in aged rats, as well as in young rats with impairments induced by scopolamine[2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease
References	[1]. Dörje F, et al. Antagonist binding profiles of five cloned human muscarinic receptor subtypes. J Pharmacol Exp Ther. 1991 Feb;256(2):727-33. [2]. Vannucchi MG, et al. Selective muscarinic antagonists differentially affect in vivo acetylcholine release and memory performances of young and aged rats. Neuroscience. 1997 Aug;79(3):837-46.

Description

Related Catalog

Signaling Pathways >> Neuronal Signaling >> mAChR

Signaling Pathways >> GPCR/G Protein >> mAChR

Research Areas >> Neurological Disease

References

[1]. Dörje F, et al. Antagonist binding profiles of five cloned human muscarinic receptor subtypes. J Pharmacol Exp Ther. 1991 Feb;256(2):727-33.

[2]. Vannucchi MG, et al. Selective muscarinic antagonists differentially affect in vivo acetylcholine release and memory performances of young and aged rats. Neuroscience. 1997 Aug;79(3):837-46.

Density	1.1±0.1 g/cm3
Boiling Point	618.4±55.0 °C at 760 mmHg
Molecular Formula	C₂₇H₃₈N₆O₂
Molecular Weight	478.630
Flash Point	327.8±31.5 °C
Exact Mass	478.305634
LogP	3.48
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.570

RIDADR	NONH for all modes of transport

MFCD00884624

N-(2-{2-[(Dipropylamino)methyl]-1-piperidinyl}ethyl)-6-oxo-5,6-dihydro-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide

N-(2-{2-[(Dipropylamino)methyl]piperidin-1-yl}ethyl)-6-oxo-5,6-dihydro-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide

11H-Pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide, N-[2-[2-[(dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-

AFDX384

DC Chemicals Limited
China
Product Name: AF-DX 384
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Get all suppliers and price by the below link:

AF-DX 384 suppliers

AF-DX 384 price

AF-DX 384

Use of AF-DX 384

Names

AF-DX 384 Biological Activity

Chemical & Physical Properties

Safety Information

Synonyms