Licarbazepine-d4-1

Modify Date: 2024-02-05 11:46:48

Licarbazepine-d4-1 structure	Common Name	Licarbazepine-d4-1
	CAS Number	1188265-49-7	Molecular Weight	258.31
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₁₀D₄N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Licarbazepine-d4-1

Licarbazepine-d4-1 is deuterium labeled Licarbazepine. Licarbazepine (BIA 2-005; GP 47779) is a voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects[1].

Name	1,2,3,4-tetradeuterio-5-hydroxy-5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide

Description	Licarbazepine-d4-1 is deuterium labeled Licarbazepine. Licarbazepine (BIA 2-005; GP 47779) is a voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Neurological Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Rajinder P Singh, et al. A review of eslicarbazepine acetate for the adjunctive treatment of partial-onset epilepsy. J Cent Nerv Syst Dis. 2011 Jul 20;3:179-87.

Molecular Formula	C₁₅H₁₀D₄N₂O₂
Molecular Weight	258.31
Exact Mass	258.13100
PSA	67.55000
LogP	3.07170