BMS-764459

Modify Date: 2024-01-02 16:42:14

BMS-764459 structure	Common Name	BMS-764459
	CAS Number	1188407-45-5	Molecular Weight	405.39900
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₂₁F₂N₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BMS-764459

BMS-764459 is a CRF1 antagonist. BMS-764459 can be used for the research of neurological disorders such as depression and anxiety. BMS-764459 is also an atypical CYP1A1 inducer[1][2].

Name	4-[(1S)-1-Cyclopropyl-2-methoxyethyl]-6-{[6-(difluoromethoxy)-2,5 -dimethyl-3-pyridinyl]amino}-5-oxo-4,5-dihydro-2-pyrazinecarbonit rile

Description	BMS-764459 is a CRF1 antagonist. BMS-764459 can be used for the research of neurological disorders such as depression and anxiety. BMS-764459 is also an atypical CYP1A1 inducer[1][2].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Signaling Pathways >> GPCR/G Protein >> CRFR Research Areas >> Neurological Disease
Target	CRF1[1], CYP1A1[2]
References	[1]. David K. Leahy, et al. Development of an Efficient Synthesis of Two CRF Antagonists for the Treatment of Neurological Disorders. Org. Process Res. Dev. 2010, 14, 5, 1221-1228. [2]. Simic D, et al. MicroRNA changes associated with atypical CYP1A1 inducer BMS-764459. Toxicology. 2013 Sep 15;311(3):169-77.

Molecular Formula	C₁₉H₂₁F₂N₅O₃
Molecular Weight	405.39900
Exact Mass	405.16100
PSA	105.29000
LogP	2.49118

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Bms-764459
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Bms-764459
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.