5-O-Desmethyl donepezil-d5

Modify Date: 2024-01-22 11:00:36

5-O-Desmethyl donepezil-d5 structure	Common Name	5-O-Desmethyl donepezil-d5
	CAS Number	1189929-21-2	Molecular Weight	370.50
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₂D₅NO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 5-O-Desmethyl donepezil-d5

5-O-Desmethyl donepezil-d5 is deuterium labeled 5-O-Desmethyl donepezil.

Name	5-hydroxy-6-methoxy-2-[[1-[(2,3,4,5,6-pentadeuteriophenyl)methyl]piperidin-4-yl]methyl]-2,3-dihydroinden-1-one
Synonym	More Synonyms

Description	5-O-Desmethyl donepezil-d5 is deuterium labeled 5-O-Desmethyl donepezil.
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Molecular Formula	C₂₃H₂₂D₅NO₃
Molecular Weight	370.50
Exact Mass	370.23000
PSA	49.77000
LogP	3.99600

5-O-Desmethyl Donepezil-d5