5-O-Desmethyl Donepezil

Modify Date: 2025-08-24 21:43:12

5-O-Desmethyl Donepezil Structure
5-O-Desmethyl Donepezil structure
Common Name 5-O-Desmethyl Donepezil
CAS Number 120013-57-2 Molecular Weight 365.465
Density 1.2±0.1 g/cm3 Boiling Point 545.3±50.0 °C at 760 mmHg
Molecular Formula C23H27NO3 Melting Point 170-172ºC
MSDS N/A Flash Point 283.6±30.1 °C

 Names

Name 2-[(1-benzylpiperidin-4-yl)methyl]-5-hydroxy-6-methoxy-2,3-dihydroinden-1-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 545.3±50.0 °C at 760 mmHg
Melting Point 170-172ºC
Molecular Formula C23H27NO3
Molecular Weight 365.465
Flash Point 283.6±30.1 °C
Exact Mass 365.199097
PSA 49.77000
LogP 4.28
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.604

 Synonyms

1H-Inden-1-one, 2,3-dihydro-5-hydroxy-6-methoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-
5-O-Desmethyl Donepezil
1H-Inden-1-one,2,3-dihydro-5-hydroxy-6-methoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]
UNII:56R452SD5N
1-Benzyl-4-[(5-hydroxy-6-methoxy-1-oxo-indan-2-yl)methylpiperidine
2-[(1-Benzyl-4-piperidinyl)methyl]-5-hydroxy-6-methoxy-1-indanone
Donepezil Impurity 28
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