6-Bromo-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran]-2-one

Modify Date: 2024-01-02 14:58:35

6-Bromo-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran]-2-one Structure
6-Bromo-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran]-2-one structure
Common Name 6-Bromo-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran]-2-one
CAS Number 1190861-43-8 Molecular Weight 282.133
Density 1.6±0.1 g/cm3 Boiling Point 437.1±45.0 °C at 760 mmHg
Molecular Formula C12H12BrNO2 Melting Point N/A
MSDS N/A Flash Point 218.1±28.7 °C

 Names

Name 6-bromospiro[1H-indole-3,4'-oxane]-2-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 437.1±45.0 °C at 760 mmHg
Molecular Formula C12H12BrNO2
Molecular Weight 282.133
Flash Point 218.1±28.7 °C
Exact Mass 281.005127
PSA 41.82000
LogP 2.76
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.648
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi
HS Code 2934999090

 Synthetic Route

~99%

6-Bromo-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran]-2-one Structure

6-Bromo-2',3',5...

CAS#:1190861-43-8

Literature: Laboratorios Almirall, S.A. Patent: EP2113503 A1, 2009 ; Location in patent: Page/Page column 24 ;

~70%

6-Bromo-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran]-2-one Structure

6-Bromo-2',3',5...

CAS#:1190861-43-8

Literature: Gonzalez-Lopez De Turiso, Felix; Shin, Youngsook; Brown, Matthew; Cardozo, Mario; Chen, Yi; Fong, David; Hao, Xiaolin; He, Xiao; Henne, Kirk; Hu, Yi-Ling; Johnson, Michael G.; Kohn, Todd; Lohman, Julia; McBride, Helen J.; McGee, Lawrence R.; Medina, Julio C.; Metz, Daniela; Miner, Kent; Mohn, Deanna; Pattaropong, Vatee; Seganish, Jennifer; Simard, Jillian L.; Wannberg, Sharon; Whittington, Douglas A.; Yu, Gang; Cushing, Timothy D. Journal of Medicinal Chemistry, 2012 , vol. 55, # 17 p. 7667 - 7685

~%

6-Bromo-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran]-2-one Structure

6-Bromo-2',3',5...

CAS#:1190861-43-8

Literature: Eastwood, Paul; Gonzalez, Jacob; Gomez, Elena; Caturla, Francisco; Balague, Cristina; Orellana, Adelina; Dominguez, Maria Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5270 - 5273

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Spiro[3H-indole-3,4'-[4H]pyran]-2(1H)-one, 6-bromo-2',3',5',6'-tetrahydro-
6-Bromo-2',3',5',6'-tetrahydrospiro[indole-3,4'-pyran]-2(1H)-one
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