Remdesivir O-desphosphate acetonide impurity

Modify Date: 2025-08-25 19:12:46

Remdesivir O-desphosphate acetonide impurity structure	Common Name	Remdesivir O-desphosphate acetonide impurity
	CAS Number	1191237-80-5	Molecular Weight	331.13
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₁₇N₅O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Remdesivir O-desphosphate acetonide impurity

Remdesivir O-desphosphate acetonide impurity is an impurity of Remdesivir. Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity and is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro[1][2].

Name	D-Altrononitrile, 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-3,4-O-(1-methylethylidene)
Synonym	More Synonyms

Description	Remdesivir O-desphosphate acetonide impurity is an impurity of Remdesivir. Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity and is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Signaling Pathways >> Anti-infection >> SARS-CoV
In Vitro	Remdesivir O-desphosphate acetonide impurity (analogue 21) is a 2′,3′-acetonide protected analogue of Remdesivir[1].
References	[1]. Dustin Siegel, et al. Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses. J Med Chem. 2017 Mar 9;60(5):1648-1661. [2]. Manli Wang, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020 Mar;30(3):269-271.

Molecular Formula	C₁₅H₁₇N₅O₄
Molecular Weight	331.13

Hazard Codes	Xi

MFCD32693253

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Remdesivir O-desphosphate acetonide impurity

Use of Remdesivir O-desphosphate acetonide impurity

Names

Biological Activity

Chemical & Physical Properties

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Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.