Dihydro Donepezil

Modify Date: 2025-08-24 21:55:58

Dihydro Donepezil Structure
Dihydro Donepezil structure
 Common Name Dihydro Donepezil
CAS Number 120012-04-6 Molecular Weight 381.50800
Density N/A Boiling Point 520.367ºC at 760 mmHg
Molecular Formula C24H31NO3 Melting Point N/A
MSDS N/A Flash Point 268.509ºC

 Use of Dihydro Donepezil


Dihydro Donepezil (Dihydro E2020) is a metabolite of Donepezil. Donepezil is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bAChE and hAChE, respectively[1].

 Names

Name 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-ol
Synonym More Synonyms

 Dihydro Donepezil Biological Activity

Description Dihydro Donepezil (Dihydro E2020) is a metabolite of Donepezil. Donepezil is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bAChE and hAChE, respectively[1].
Related Catalog
References

[1]. Ogura, H., et al., Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro. Methods Find Exp Clin Pharmacol, 2000. 22(8): p. 609-13.

 Chemical & Physical Properties

Boiling Point 520.367ºC at 760 mmHg
Molecular Formula C24H31NO3
Molecular Weight 381.50800
Flash Point 268.509ºC
Exact Mass 381.23000
PSA 41.93000
LogP 4.14970
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.587
InChIKey UGTUAFCYSWJIHS-UHFFFAOYSA-N
SMILES COc1cc2c(cc1OC)C(O)C(CC1CCN(Cc3ccccc3)CC1)C2

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

IND032
Dihydro Donepezil
Donepezil Impurity 5
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Chemsrc provides Dihydro Donepezil(CAS#:120012-04-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Dihydro Donepezil are included as well.>> amp version: Dihydro Donepezil

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