4-Chloro-3-sulfamoylbenzoic acid

Modify Date: 2024-01-03 07:50:02

4-Chloro-3-sulfamoylbenzoic acid structure	Common Name	4-Chloro-3-sulfamoylbenzoic acid
	CAS Number	1205-30-7	Molecular Weight	235.645
	Density	1.6±0.1 g/cm3	Boiling Point	502.4±60.0 °C at 760 mmHg
	Molecular Formula	C₇H₆ClNO₄S	Melting Point	256-258 °C(lit.)
	MSDS	Chinese USA	Flash Point	257.6±32.9 °C
	Symbol	GHS07	Signal Word	Warning

Name	4-Chloro-5-sulphamoylbenzoic acid
Synonym	More Synonyms

Density	1.6±0.1 g/cm3
Boiling Point	502.4±60.0 °C at 760 mmHg
Melting Point	256-258 °C(lit.)
Molecular Formula	C₇H₆ClNO₄S
Molecular Weight	235.645
Flash Point	257.6±32.9 °C
Exact Mass	234.970612
PSA	105.84000
LogP	0.92
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.622
Storage condition	Refrigerator

4-Chloro-3-sulfamoylbenzoic acid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG5642600

CHEMICAL NAME :: Benzoic acid, 4-chloro-3-sulfamoyl-

CAS REGISTRY NUMBER :: 1205-30-7

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H6-Cl-N-O4-S

MOLECULAR WEIGHT :: 235.65

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1100 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 16,2275,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 16,2275,1982

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	DG5642600

4-Chlorobenzoic acid

CAS#:74-11-3

4-Chloro-3-sulf...

CAS#:1205-30-7

Literature: J. Med. Chem., , vol. 6, p. 272 - 275

Precursor 1
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DownStream 6
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Studies on metabolism of tripamide. III. Metabolic fate of 14C-tripamide in rats and rabbits.

Jpn. J. Pharmacol. 32(6) , 1041-9, (1982)

The metabolic fate of a new antihypertensive agent, tripamide (N-(4-aza-endo-tricyclo[5.2.1.0(2,6))]-decan-4-yl)-4-chloro-3-sulfamoylbenzamide), in rats and rabbits was studied using its 14C-labeled c...

Chromatographic-densitometric Method for Determination of Clopamide and 4-chlorobenzoic, and 4-chloro-3-sulfamoylbenzoic Acids in Tablets. Hubicka U, et al.

Curr. Pharm. Anal. 5(4) , 408-15, (2009)

Benzoic acid, 3-(aminosulfonyl)-4-chloro-

EINECS 214-882-1

4-Chloro-3-sulfamoylbenzoic acid

MFCD00012375

3-(aminosulfonyl)-4-chlorobenzoic acid