4-Chloro-3-sulfamoylbenzoic acid

Modify Date: 2024-01-03 07:50:02

4-Chloro-3-sulfamoylbenzoic acid Structure
4-Chloro-3-sulfamoylbenzoic acid structure
Common Name 4-Chloro-3-sulfamoylbenzoic acid
CAS Number 1205-30-7 Molecular Weight 235.645
Density 1.6±0.1 g/cm3 Boiling Point 502.4±60.0 °C at 760 mmHg
Molecular Formula C7H6ClNO4S Melting Point 256-258 °C(lit.)
MSDS Chinese USA Flash Point 257.6±32.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4-Chloro-5-sulphamoylbenzoic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 502.4±60.0 °C at 760 mmHg
Melting Point 256-258 °C(lit.)
Molecular Formula C7H6ClNO4S
Molecular Weight 235.645
Flash Point 257.6±32.9 °C
Exact Mass 234.970612
PSA 105.84000
LogP 0.92
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.622
Storage condition Refrigerator

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG5642600
CHEMICAL NAME :
Benzoic acid, 4-chloro-3-sulfamoyl-
CAS REGISTRY NUMBER :
1205-30-7
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C7-H6-Cl-N-O4-S
MOLECULAR WEIGHT :
235.65

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1100 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 16,2275,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 16,2275,1982

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DG5642600

 Synthetic Route

~%

4-Chloro-3-sulfamoylbenzoic acid Structure

4-Chloro-3-sulf...

CAS#:1205-30-7

Literature: J. Med. Chem., , vol. 6, p. 272 - 275

 Articles2

More Articles
Studies on metabolism of tripamide. III. Metabolic fate of 14C-tripamide in rats and rabbits.

Jpn. J. Pharmacol. 32(6) , 1041-9, (1982)

The metabolic fate of a new antihypertensive agent, tripamide (N-(4-aza-endo-tricyclo[5.2.1.0(2,6))]-decan-4-yl)-4-chloro-3-sulfamoylbenzamide), in rats and rabbits was studied using its 14C-labeled c...

Chromatographic-densitometric Method for Determination of Clopamide and 4-chlorobenzoic, and 4-chloro-3-sulfamoylbenzoic Acids in Tablets. Hubicka U, et al.

Curr. Pharm. Anal. 5(4) , 408-15, (2009)

 Synonyms

Benzoic acid, 3-(aminosulfonyl)-4-chloro-
EINECS 214-882-1
4-Chloro-3-sulfamoylbenzoic acid
MFCD00012375
3-(aminosulfonyl)-4-chlorobenzoic acid
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