AV-105
Modify Date: 2024-01-10 10:52:19
AV-105 structure
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Common Name | AV-105 | ||
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| CAS Number | 1205550-99-7 | Molecular Weight | 612.73400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C32H40N2O8S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AV-105AV-105 is a Florbetapir (18F)-radiolabeled slyrylpyridine tosylate precursor extracted from patent WO2010078370A1, example 1.5. AV-105 can synthesize 18F-radiolabeled compounds, which are used for positron emission tomography (PET) imaging of neurodegenerative diseases of the brain[1]. |
| Name | (E)-2-[2-[2-[5-[4-[tert-butoxycarbonyl[methyl]amino]styryl]pyridine-2-yloxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate |
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| Synonym | More Synonyms |
| Description | AV-105 is a Florbetapir (18F)-radiolabeled slyrylpyridine tosylate precursor extracted from patent WO2010078370A1, example 1.5. AV-105 can synthesize 18F-radiolabeled compounds, which are used for positron emission tomography (PET) imaging of neurodegenerative diseases of the brain[1]. |
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| Related Catalog | |
| In Vitro | The AV-105 synthesis method utilizes a primary tosylate instead of a primary mesylate as an active leaving group. Use of the tosylate precursor for radiofluorination is beneficial, at least for the reason that the tosylate generated during the radiofluorination reaction is readily removed by chromatographic means from the 18F-radiolabeled imaging product[1]. |
| References |
| Molecular Formula | C32H40N2O8S |
|---|---|
| Molecular Weight | 612.73400 |
| Exact Mass | 612.25100 |
| PSA | 121.87000 |
| LogP | 6.83000 |
| Precursor 0 | |
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| DownStream 1 | |
CAS#:956103-76-7| .(E)-2-(2-(2-(5-(4-(tert-butoxycarbonyl(methyl)amino)styryl)pyridin-2-yloxy)ethoxy)ethoxy)ethyl 4-methylbenzenesulfonate |
| AV-105 |