GLPG0634 structure
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Common Name | GLPG0634 | ||
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CAS Number | 1206101-20-3 | Molecular Weight | 410.428 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
Molecular Formula | C23H18N6O2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of GLPG0634GLPG0634 (analog) (compound176)is a pan JAK inhibitor with IC50s of 50-200 nM for JAK1/JAK2/JAK3; more information can be found in the reference patents. |
Name | N-(5-{4-[(6-Cyano-3-pyridinyl)methoxy]phenyl}[1,2,4]triazolo[1,5- a]pyridin-2-yl)cyclopropanecarboxamide |
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Synonym | More Synonyms |
Description | GLPG0634 (analog) (compound176)is a pan JAK inhibitor with IC50s of 50-200 nM for JAK1/JAK2/JAK3; more information can be found in the reference patents. |
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Related Catalog | |
Target |
JAK3:<100 nM (IC50) Tyk2:<100 nM (IC50) |
References |
[1]. http://www.google.com/patents/WO2013173506A2cl=en |
Density | 1.4±0.1 g/cm3 |
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Molecular Formula | C23H18N6O2 |
Molecular Weight | 410.428 |
Exact Mass | 410.149109 |
PSA | 108.43000 |
LogP | 2.26 |
Index of Refraction | 1.733 |
Storage condition | -20℃ |
Hazard Codes | Xi |
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~% GLPG0634 CAS#:1206101-20-3 |
Literature: Menet, Christel Jeanne Marie; Blanc, Javier Patent: US2010/29709 A1, 2010 ; Location in patent: Page/Page column 26 ; |
Precursor 1 | |
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DownStream 0 |
N-(5-{4-[(6-Cyano-3-pyridinyl)methoxy]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide |
Cyclopropanecarboxamide, N-[5-[4-[(6-cyano-3-pyridinyl)methoxy]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]- |
GLPG0634 |
GLPG0634 analogue |
GLPG0634 analog |