Gallinamide A

Modify Date: 2024-01-17 22:04:35

Gallinamide A Structure
Gallinamide A structure
Common Name Gallinamide A
CAS Number 1208232-55-6 Molecular Weight 592.77
Density 1.1±0.1 g/cm3 Boiling Point 747.8±60.0 °C at 760 mmHg
Molecular Formula C31H52N4O7 Melting Point N/A
MSDS N/A Flash Point 406.1±32.9 °C

 Use of Gallinamide A


Gallinamide A is a potent inhibitor of cathepsin L with an IC50 value of 17.6 pM.

 Names

Name symplostatin 4
Synonym More Synonyms

 Gallinamide A Biological Activity

Description Gallinamide A is a potent inhibitor of cathepsin L with an IC50 value of 17.6 pM.
Related Catalog
References

[1]. Ashhurst AS, et al. Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L. bioRxiv [Preprint]. 2020 Dec 24:2020.12.23.424111.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 747.8±60.0 °C at 760 mmHg
Molecular Formula C31H52N4O7
Molecular Weight 592.77
Flash Point 406.1±32.9 °C
Exact Mass 592.383606
LogP 5.48
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.522

 Synonyms

symplostatin 4
Isoleucine, N,N-dimethyl-, 1-[[[1-[[[(2E)-4-(2,5-dihydro-3-methoxy-2-methyl-5-oxo-1H-pyrrol-1-yl)-1-methyl-4-oxo-2-buten-1-yl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-3-methylbutyl ester
1-[(1-{[(3E)-5-(3-Methoxy-2-methyl-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-5-oxo-3-penten-2-yl]amino}-4-methyl-1-oxo-2-pentanyl)amino]-4-methyl-1-oxo-2-pentanyl N,N-dimethylisoleucinate