IEM-1460

Modify Date: 2025-08-26 17:18:16

IEM-1460 structure	Common Name	IEM-1460
	CAS Number	121034-89-7	Molecular Weight	454.33
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₃₈Br₂N₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of IEM-1460

IEM-1460 blocks both AMPA and NMDA glutamate receptor with anticonvulsant effect in vivo[1].

Name	5-(1-adamantylmethylamino)pentyl-trimethylazanium,bromide,hydrobromide
Synonym	More Synonyms

Description	IEM-1460 blocks both AMPA and NMDA glutamate receptor with anticonvulsant effect in vivo[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
References	[1]. Schlesinger F, et al. Two mechanisms of action of the adamantane derivative IEM-1460 at human AMPA-type glutamate receptors. Br J Pharmacol. 2005 Jul;145(5):656-63.

Molecular Formula	C₁₉H₃₈Br₂N₂
Molecular Weight	454.33
Exact Mass	452.140167
PSA	12.03000
LogP	2.02190
InChIKey	CQTDZUSQSTUZDA-UHFFFAOYSA-M
SMILES	Br.C[N+](C)(C)CCCCCNCC12CC3CC(CC(C3)C1)C2.[Br-]

Name: Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro...
Source: NCGC
Target: N/A
External Id: SERCaMPGLuc-p1-antagonist

Name: Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 3 (E...
Source: NCGC
External Id: epac1-activator-v

Name: Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 3...
Source: NCGC
External Id: epac1-inhibitor-v

Name: Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 4 (E...
Source: NCGC
External Id: epac2-activator-v2

Name: Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 4...
Source: NCGC
External Id: epac2-inhibitor-v2

Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100

Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101

Name: qHTS for Inhibitors of Polymerase Kappa
Source: NCGC
Target: DNA polymerase kappa [Homo sapiens]
External Id: PolK100

Name: Tocris HTS for Inhibitors of Aerobactin Synthetase lucA
Source: 23265
External Id: IucA Pilot Assay Tocris Library

Name: LOPAC HTS for Inhibitors of Aerobactin Synthetase IucA
Source: 23265
Target: IucA from hypervirulent Klebsiella pneumoniae
External Id: IucA Pilot Assay LOPAC Library

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5-[(Adamantan-1-ylmethyl)amino]-N,N,N-trimethyl-1-pentanaminium bromide hydrobromide (1:1:1)

1-Pentanaminium, N,N,N-trimethyl-5-[(tricyclo[3.3.1.1]dec-1-ylmethyl)amino]-, bromide, hydrobromide (1:1:1)

5-[(Adamantan-1-ylmethyl)amino]-N,N,N-trimethylpentan-1-aminium bromide hydrobromide (1:1:1)

Iem 1460

Tocris-1636

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: IEM-1460
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

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Chemical & Physical Properties

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Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.