H-Leu-Pro-Pro-OH

Modify Date: 2025-08-25 21:16:27

H-Leu-Pro-Pro-OH Structure
H-Leu-Pro-Pro-OH structure
 Common Name H-Leu-Pro-Pro-OH
CAS Number 121305-26-8 Molecular Weight 325.40300
Density 1.247g/cm3 Boiling Point 572.6ºC at 760mmHg
Molecular Formula C16H27N3O4 Melting Point N/A
MSDS N/A Flash Point 300.1ºC

 Use of H-Leu-Pro-Pro-OH


LPP Tripeptide is a blood pressure lowering tripeptides. LPP Tripeptide can be used for research of hypertension[1].

 Names

Name (2S)-1-[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid
Synonym More Synonyms

 H-Leu-Pro-Pro-OH Biological Activity

Description LPP Tripeptide is a blood pressure lowering tripeptides. LPP Tripeptide can be used for research of hypertension[1].
Related Catalog
References

[1]. van der Pijl PC, et al. Pharmacokinetics of proline-rich tripeptides in the pig. Peptides. 2008 Dec;29(12):2196-202.  

 Chemical & Physical Properties

Density 1.247g/cm3
Boiling Point 572.6ºC at 760mmHg
Molecular Formula C16H27N3O4
Molecular Weight 325.40300
Flash Point 300.1ºC
Exact Mass 325.20000
PSA 103.94000
LogP 1.00250
Vapour Pressure 1.33E-14mmHg at 25°C
Index of Refraction 1.556
InChIKey DPURXCQCHSQPAN-AVGNSLFASA-N
SMILES CC(C)CC(N)C(=O)N1CCCC1C(=O)N1CCCC1C(=O)O

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TW3675000
CHEMICAL NAME :
L-Proline, 1-(1-L-leucyl-L-prolyl)-
CAS REGISTRY NUMBER :
121305-26-8
LAST UPDATED :
199506
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H27-N3-O4
MOLECULAR WEIGHT :
325.46

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #90-240027

 Synonyms

1-(1-L-Leucyl-L-prolyl)-L-proline
L-Proline,1-(1-L-leucyl-L-prolyl)
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