N-ε-propargyloxycarbonyl-L-lysine

Modify Date: 2024-01-08 17:34:02

N-ε-propargyloxycarbonyl-L-lysine Structure
N-ε-propargyloxycarbonyl-L-lysine structure
Common Name N-ε-propargyloxycarbonyl-L-lysine
CAS Number 1215204-46-8 Molecular Weight 228.24504
Density N/A Boiling Point N/A
Molecular Formula C10H16N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-ε-propargyloxycarbonyl-L-lysine


N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals[1][2].

 Names

Name (2S)-2-amino-6-{[(prop-2-yn-1-yloxy)carbonyl]amino}hexanoic acid

 N-ε-propargyloxycarbonyl-L-lysine Biological Activity

Description N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals[1][2].
Related Catalog
In Vitro Labeling of N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH)-carrying cellular proteins, such as Sec61β, Htt74Q and the histone H3 variant H3.3, with a sensitive Raman tag by click chemistry for molecular hyperspectral SRS imaging[1].
References

[1]. Kyung Jin Lee, et al. Site-Specific Labeling of Proteins Using Unnatural Amino Acids. Mol Cells. 2019 May 31;42(5):386-396.

[2]. Enke HEIKE, et al. Modified microcystins and nodularins.WO2018206715A2

 Chemical & Physical Properties

Molecular Formula C10H16N2O4
Molecular Weight 228.24504