AR-AO 14418-d3

Modify Date: 2025-09-11 17:27:47

AR-AO 14418-d3 structure	Common Name	AR-AO 14418-d3
	CAS Number	1216908-63-2	Molecular Weight	308.31308
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₁₂N₄O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AR-AO 14418-d3

AR-A014418-d3 (AR 0133418-d3) is the deuterium labeled AR-A014418. AR-A014418 is a potent, selective, and ATP-competitive GSK3β inhibitor (IC50=104 nM; Ki=38 nM)[1].

Name	AR-AO 14418-d3

Description	AR-A014418-d3 (AR 0133418-d3) is the deuterium labeled AR-A014418. AR-A014418 is a potent, selective, and ATP-competitive GSK3β inhibitor (IC50=104 nM; Ki=38 nM)[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> GSK-3 Research Areas >> Cancer Research Areas >> Metabolic Disease Signaling Pathways >> PI3K/Akt/mTOR >> GSK-3
References	[1]. Bhat R, Xue Y, Berg S, Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418. J Biol Chem. 2003 Nov 14;278(46):45937-45.

Molecular Formula	C₁₂H₁₂N₄O₄S
Molecular Weight	308.31308
InChIKey	YAEMHJKFIIIULI-FIBGUPNXSA-N
SMILES	COc1ccc(CNC(=O)Nc2ncc([N+](=O)[O-])s2)cc1
Storage condition	2-8°C

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: AR-AO 14418-d3
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Purity: 98.0%
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