(-)-Ibuprofenamide

Modify Date: 2024-01-09 16:38:25

(-)-Ibuprofenamide structure	Common Name	(-)-Ibuprofenamide
	CAS Number	121839-78-9	Molecular Weight	205.30
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₃H₁₉NO	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (-)-Ibuprofenamide

(-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity[1]. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[2].

Name	(2R)-2-[4-(2-methylpropyl)phenyl]propanamide
Synonym	More Synonyms

Description	(-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity[1]. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	COX-1, COX-2[2]
References	[1]. Shanbhag VR, et al. Ester and amide prodrugs of ibuprofen and naproxen: synthesis, anti-inflammatory activity, and gastrointestinal toxicity. J Pharm Sci. 1992 Feb;81(2):149-54. [2]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7.

Molecular Formula	C₁₃H₁₉NO
Molecular Weight	205.30
Exact Mass	205.14700
PSA	43.09000
LogP	3.17420

(R)-2-(4-Isobutyl-phenyl)-propionamide

(R)-2-(4-isobutylphenyl)propionamide

(-)-Ibuprofenamide

Use of (-)-Ibuprofenamide

Names

(-)-Ibuprofenamide Biological Activity

Chemical & Physical Properties

Synonyms