(-)-Ibuprofenamide

Modify Date: 2024-01-09 16:38:25

(-)-Ibuprofenamide structure	Common Name	(-)-Ibuprofenamide
	CAS Number	121839-78-9	Molecular Weight	205.30
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₃H₁₉NO	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (-)-Ibuprofenamide

(-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity[1]. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[2].

Name	(2R)-2-[4-(2-methylpropyl)phenyl]propanamide
Synonym	More Synonyms

Description	(-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity[1]. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	COX-1, COX-2[2]
References	[1]. Shanbhag VR, et al. Ester and amide prodrugs of ibuprofen and naproxen: synthesis, anti-inflammatory activity, and gastrointestinal toxicity. J Pharm Sci. 1992 Feb;81(2):149-54. [2]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7.

Molecular Formula	C₁₃H₁₉NO
Molecular Weight	205.30
Exact Mass	205.14700
PSA	43.09000
LogP	3.17420

(R)-2-(4-Isobutyl-phenyl)-propionamide

(R)-2-(4-isobutylphenyl)propionamide

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(-)-Ibuprofenamide

Use of (-)-Ibuprofenamide

Names

(-)-Ibuprofenamide Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.