4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene

Modify Date: 2024-01-03 00:16:49

4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene Structure
4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene structure
Common Name 4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene
CAS Number 1222-05-5 Molecular Weight 258.398
Density 0.9±0.1 g/cm3 Boiling Point 326.3±11.0 °C at 760 mmHg
Molecular Formula C18H26O Melting Point N/A
MSDS Chinese USA Flash Point 146.1±15.5 °C
Symbol GHS09
GHS09
Signal Word Warning

 Names

Name galaxolide
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 326.3±11.0 °C at 760 mmHg
Molecular Formula C18H26O
Molecular Weight 258.398
Flash Point 146.1±15.5 °C
Exact Mass 258.198364
PSA 9.23000
LogP 6.23
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.499

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GY0790000
CHEMICAL NAME :
Cyclopenta(g)-2-benzopyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-
CAS REGISTRY NUMBER :
1222-05-5
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C18-H26-O
MOLECULAR WEIGHT :
258.44
WISWESSER LINE NOTATION :
T C566 KOT&TJ D1 D1 E1 E1 F1 F1 M1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,793,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0055 No. of Facilities: 15 (estimated) No. of Industries: 1 No. of Occupations: 16 No. of Employees: 2279 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0055 No. of Facilities: 3202 (estimated) No. of Industries: 10 No. of Occupations: 11 No. of Employees: 32968 (estimated) No. of Female Employees: 20222 (estimated)

 Safety Information

Symbol GHS09
GHS09
Signal Word Warning
Hazard Statements H410
Precautionary Statements P273-P391-P501
Personal Protective Equipment Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Hazard Codes Xi: Irritant;N: Dangerous for the environment;
Risk Phrases R38
Safety Phrases S26-S36
RIDADR UN 3082 9 / PGIII
WGK Germany 3
HS Code 2932999099

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles28

More Articles
Metabolism of the polycyclic musk galaxolide and its interference with endogenous and xenobiotic metabolizing enzymes in the European sea bass (Dicentrarchus labrax).

Environ. Pollut. 174 , 214-21, (2013)

This study investigates the metabolism and mode of action of galaxolide (HHCB) in the European sea bass -Dicentrarchus labrax- following a single intraperitoneal injection of 50 mg HHCB/kg body weight...

Simultaneous detection and quantification of select nitromusks, antimicrobial agent, and antihistamine in fish of grocery stores by gas chromatography-mass spectrometry.

Chemosphere 107 , 187-93, (2014)

Continually detected biologically persistent nitromusks; galaxolide (HHCB), tonalide (AHTN) and musk ketone (MK), antimicrobial triclosan (TCS), and antihistamine diphenhydramine (DPH) were examined f...

Levels of synthetic musk fragrances in human milk from three cities in the Yangtze River Delta in Eastern China.

J. Environ. Sci. (China) 23(6) , 983-90, (2011)

Synthetic musks are used as additives in many household products. After absorption into the human body, they accumulate and their concentrations in human milk reflect both the mother and her infant's ...

 Synonyms

Cyclopenta[g]-2-benzopyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-
ABBALIDE
Galoxolide
7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthalene
7-acetyl-1,1,3,4,4,6-hexamethyltetraline
EINECS 214-946-9
5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl-ethanone
7-acetyl-1,1,3,4,4,6-hexamethyl-tetrahydronaphthalene
8-hexamethylcyclopenta[g]-2-benzopyran
MFCD00217003
6-acetyl-1,1,2,4,4,7-hexamethyl-tetralin
Musk50
4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene
1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran
8-Hexahydro-4
PEARLIDE PURE
Pearlide
Galaxolide
Indeno[5,6-c]pyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-
6-acetyl-1,1,2,4,4,7-hexamethyl-1,2,3,4-tetrahydronaphthalene
HHCB
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