4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene
![4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene Structure](https://image.chemsrc.com/caspic/497/1222-05-5.png)
4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene structure
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Common Name | 4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene | ||
|---|---|---|---|---|
| CAS Number | 1222-05-5 | Molecular Weight | 258.398 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 326.3±11.0 °C at 760 mmHg | |
| Molecular Formula | C18H26O | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 146.1±15.5 °C | |
| Symbol |
GHS09 |
Signal Word | Warning | |
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Metabolism of the polycyclic musk galaxolide and its interference with endogenous and xenobiotic metabolizing enzymes in the European sea bass (Dicentrarchus labrax).
Environ. Pollut. 174 , 214-21, (2013) This study investigates the metabolism and mode of action of galaxolide (HHCB) in the European sea bass -Dicentrarchus labrax- following a single intraperitoneal injection of 50 mg HHCB/kg body weight. In addition, a group of fish was injected with 50 mg/kg o... |
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Simultaneous detection and quantification of select nitromusks, antimicrobial agent, and antihistamine in fish of grocery stores by gas chromatography-mass spectrometry.
Chemosphere 107 , 187-93, (2014) Continually detected biologically persistent nitromusks; galaxolide (HHCB), tonalide (AHTN) and musk ketone (MK), antimicrobial triclosan (TCS), and antihistamine diphenhydramine (DPH) were examined for the first time in edible fillets originating from eight ... |
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Levels of synthetic musk fragrances in human milk from three cities in the Yangtze River Delta in Eastern China.
J. Environ. Sci. (China) 23(6) , 983-90, (2011) Synthetic musks are used as additives in many household products. After absorption into the human body, they accumulate and their concentrations in human milk reflect both the mother and her infant's exposure level. Concentrations of four synthetic musks, mus... |
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Development of a stir bar sorptive extraction and thermal desorption-gas chromatography-mass spectrometry method for determining synthetic musks in water samples.
J. Chromatogr. A. 1218(1) , 156-61, (2011) This study presents the development of an analytical method for determining 9 synthetic musks in water matrices. The developed method is based on stir bar sorptive extraction (SBSE), coated with polydimethylsiloxane, and coupled with a thermal desorption-gas ... |
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The occurrence of synthetic musks in human breast milk in Sichuan, China.
Chemosphere 87(9) , 1018-23, (2012) Human breast milk samples collected from mothers (n=110) who lived in Chengdu, Sichuan Province, southwestern China in 2009 were analyzed to determine the concentrations of 13 musk compounds. Possible relationships between musk concentrations and some persona... |
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Read-across estimates of aquatic toxicity for selected fragrances.
Altern. Lab. Anim. 41(1) , 77-90, (2013) Read-across as a non-animal testing alternative for the generation of risk assessment data can be useful in those cases where quantitative structure-activity relationship (QSAR) models are not available, or are less well developed. This paper provides read-ac... |
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High-sensitivity analysis of six synthetic musks by ultra-performance liquid chromatography-atmospheric pressure photoionization-tandem mass spectrometry.
Anal. Chem. 83(12) , 4955-61, (2011) The occurrence and potential toxicity of synthetic musks in environmental media have aroused concerns for the impacts of these chemicals on ecosystems and human health. Here, we present the first method using ultra-performance liquid chromatography-atmospheri... |
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Transformation products and reaction kinetics of fragrances in advanced wastewater treatment with ozone.
Chemosphere 85(9) , 1481-6, (2011) The reaction of the fragrance compounds 4,6,6,7,8,8-hexamethyl-1,3,4,7-tetrahydrocyclopenta[g]isochromene (HHCB), 1-(3,5,5,6,8,8-hexamethyl-6,7-dihydronaphthalen-2-yl)ethanone (AHTN), 1-tert-butyl-3,5-dimethyl-2,4,6-trinitrobenzene (musk xylene/MX), 1-(4-tert... |
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A genome-wide study on the perception of the odorants androstenone and galaxolide.
Chem. Senses 37(6) , 541-52, (2012) Twin pairs and their siblings rated the intensity of the odorants amyl acetate, androstenone, eugenol, Galaxolide, mercaptans, and rose (N = 1573). Heritability was established for ratings of androstenone (h (2) = 0.30) and Galaxolide (h(2) = 0.34) but not fo... |
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Ecotoxicological responses of the earthworm Eisenia fetida exposed to soil contaminated with HHCB.
Chemosphere 83(8) , 1080-6, (2011) Although polycyclic musks have been shown to cause lethal and sub-lethal effects on organisms, their biochemical toxicity to earthworms is not well understood. In the current study, we investigated the responses of antioxidant systems and lipid peroxidation a... |