Trichostatin A S-isomer

Modify Date: 2024-01-17 21:08:49

Trichostatin A S-isomer Structure
Trichostatin A S-isomer structure
 Common Name Trichostatin A S-isomer
CAS Number 122292-85-7 Molecular Weight 302.36800
Density N/A Boiling Point N/A
Molecular Formula C17H22N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name Trichostatin A
Synonym More Synonyms

 Trichostatin A S-isomer Biological Activity

Description (S)-Trichostatin A ((S)-TSA) 是一种 HDAC6 选择性抑制剂，对斑马鱼 HDAC6 和人 HDAC6 的 IC50 值分别为 9.88 nM和 11.1 nM。(S)-Trichostatin A 弱抑制其他人 HDAC。
Related Catalog
Target

hHDAC6:11.1 nM (IC50)

Zebrafish HDAC6:9.88 nM (IC50)

hHDAC1:206.3 nM (IC50)

hHDAC2:612.65 nM (IC50)

hHDAC3:320.8 nM (IC50)

hHDAC4:6341 nM (IC50)

hHDAC5:6325 nM (IC50)

hHDAC7:1823.5 nM (IC50)

hHDAC8:312.2 nM (IC50)

hHDAC9:4824 nM (IC50)

hHDAC10:403.35 nM (IC50)

hHDAC11:2684 nM (IC50)

References

[1]. Yasuyuki Miyake, et al. Structural insights into HDAC6 tubulin deacetylation and its selective inhibition. Nat Chem Biol. 2016 Sep;12(9):748-54.  

 Chemical & Physical Properties

Molecular Formula C17H22N2O3
Molecular Weight 302.36800
Exact Mass 302.16300
PSA 69.64000
LogP 2.97020

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

.TSA
.(R)-trichostatin A
.(R)-(+)-trichostatin A
.(7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide)
(+)-TSA
Top Suppliers:I want be here

Get all suppliers and price by the below link:

Trichostatin A S-isomer suppliers

Trichostatin A S-isomer price

Related Compounds: More...
Trichostatin A
58880-19-6
S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (4E,7E,10E,13E,16E)-icosa-4,7,10,13,16-pentaenethioa
121935-04-4
(4R)-5-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethylsulfanyl]-4-hydroxy-5-oxopentanoic acid
111769-66-5
[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(3R)-4-[[3-(2-dimethylarsanylsulfanylethylamino)-3-oxopropyl]amino]-3-hydroxy-2,2-dimethyl-4-oxobutyl] hydrogen phosphate
88978-30-7
Exiguaflavanone A
142608-98-8
S-[2-[3-[[(2R)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] dodec-3-enethioate
2152-91-2
Coenzyme A, S-(2-carboxy-γ-oxobenzenebutanoate)
97226-61-4
Coenzyme A, S-(15Z)-15-tetracosenoate
88362-35-0
trifarienol A
159359-53-2
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1158522-08-7
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
940364-43-2
1-{5-Fluoro-6-[(3-methoxyphenyl)methyl]pyrimidin-4-yl}methanamine
2448160-49-2
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
134104-43-1
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
131615-57-1
(4-Methyl-tetrahydro-furan-2-yl)-methanol
6906-52-1
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
930439-75-1
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
1018584-77-4
tert-Butyl-DL-alanine
1375289-11-4
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
849349-65-1
Chemsrc provides Trichostatin A S-isomer(CAS#:122292-85-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Trichostatin A S-isomer are included as well.>> amp version: Trichostatin A S-isomer

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved