Fenbendazole-d3

Modify Date: 2024-01-14 14:24:30

Fenbendazole-d3 Structure
Fenbendazole-d3 structure
Common Name Fenbendazole-d3
CAS Number 1228182-47-5 Molecular Weight 302.36600
Density N/A Boiling Point 209-216 °C
Molecular Formula C15H10D3N3O2S Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of Fenbendazole-d3


Fenbendazole-d3 is a deuterium labeled Fenbendazole. Fenbendazole is a benzimidazole anthelmintic. Fenbendazole is active against Giardia in vitro (IC50 = 0.3 μM). Fenbendazole (20 mg/kg) prevents infiltration of parasites into the brain in a rabbit model of E. cuniculi infection. Fenbendazole also activates HIF-1α and prevents oxidative stress-induced death in primary neurons in vitro.

 Names

Name trideuteriomethyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate
Synonym More Synonyms

 Fenbendazole-d3 Biological Activity

Description Fenbendazole-d3 is a deuterium labeled Fenbendazole. Fenbendazole is a benzimidazole anthelmintic. Fenbendazole is active against Giardia in vitro (IC50 = 0.3 μM). Fenbendazole (20 mg/kg) prevents infiltration of parasites into the brain in a rabbit model of E. cuniculi infection. Fenbendazole also activates HIF-1α and prevents oxidative stress-induced death in primary neurons in vitro.
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 Chemical & Physical Properties

Boiling Point 209-216 °C
Molecular Formula C15H10D3N3O2S
Molecular Weight 302.36600
Exact Mass 302.09200
PSA 95.80000
LogP 3.90600

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Synonyms

Axilur-d3
2-[(Methoxy-d3)carbonylamino]-5-(phenylthio)benzimidazole
Fenbendazole-d3
HOE 881-d3
Methyl-d3 5-(phenylthio)-2-benzimidazolecarbamate
Safe-Guard-d3
Fenbendazol-d3
Panacur-d3
Fenbion-d3