Acetyl-Calpastatin (184-210) (human) trifluoroacetate salt

Modify Date: 2024-01-19 15:44:42

Acetyl-Calpastatin (184-210) (human) trifluoroacetate salt structure	Common Name	Acetyl-Calpastatin (184-210) (human) trifluoroacetate salt
	CAS Number	123714-50-1	Molecular Weight	3177.63000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄₂H₂₃₀N₃₆O₄₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Acetyl-Calpastatin (184-210) (human) trifluoroacetate salt

Acetyl-Calpastatin(184-210)(human) is a potent, selective and reversible calpain inhibitor with Ki values of 0.2 nM and 6 μM for µ-calpain and cathepsin L, respectively[1][2].

Name	Acetyl-Calpastatin (184-210) (human)

Description	Acetyl-Calpastatin(184-210)(human) is a potent, selective and reversible calpain inhibitor with Ki values of 0.2 nM and 6 μM for µ-calpain and cathepsin L, respectively[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome
In Vitro	Acetyl-Calpastatin(184-210)(human) (peptide 1; 12.5-100 μM) inhibits calpains in LCLC 103H cells with an IC50 of 27 μM[1].
References	[1]. Ferdinando Fiorino, et al. A new cell-permeable calpain inhibitor. J Pept Sci. 2007 Jan;13(1):70-3. [2]. Benjamin P Davis, et al. Eosinophilic esophagitis-linked calpain 14 is an IL-13-induced protease that mediates esophageal epithelial barrier impairment. JCI Insight. 2016 Apr;1(4):e86355.

Molecular Formula	C₁₄₂H₂₃₀N₃₆O₄₄S
Molecular Weight	3177.63000
Exact Mass	3175.66000
PSA	1311.44000
LogP	3.43000
Appearance of Characters	powder
Storage condition	−20°C
Water Solubility	H2O: 1 mg/mL

WGK Germany	3

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Acetyl-Calpastatin (184-210) (human) trifluoroacetate salt
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Acetyl-Calpastatin(184-210)(human)
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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