NCDM-32B

Modify Date: 2024-01-09 19:19:46

NCDM-32B Structure
NCDM-32B structure
Common Name NCDM-32B
CAS Number 1239468-48-4 Molecular Weight 302.41
Density N/A Boiling Point N/A
Molecular Formula C15H30N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NCDM-32B


NCDM-32B is a potent and selective KDM4 inhibitor that impaires viability and transforming phenotypes of breast cancer[1].

 Names

Name methyl 3-[9-(dimethylamino)nonanoyl-hydroxyamino]propanoate
Synonym More Synonyms

 NCDM-32B Biological Activity

Description NCDM-32B is a potent and selective KDM4 inhibitor that impaires viability and transforming phenotypes of breast cancer[1].
Related Catalog
References

[1]. Ye Q, et al. Genetic alterations of KDM4 subfamily and therapeutic effect of novel demethylase inhibitor in breast cancer. Am J Cancer Res. 2015 Mar 15;5(4):1519-30.

 Chemical & Physical Properties

Molecular Formula C15H30N2O4
Molecular Weight 302.41
Exact Mass 302.22100
PSA 70.08000
LogP 2.05960

 Synthetic Route

~93%

NCDM-32B Structure

NCDM-32B

CAS#:1239468-48-4

Literature: Hamada, Shohei; Suzuki, Takayoshi; Mino, Koshiki; Koseki, Koichi; Oehme, Felix; Flamme, Ingo; Ozasa, Hiroki; Itoh, Yukihiro; Ogasawara, Daisuke; Komaarashi, Haruka; Kato, Aiko; Tsumoto, Hiroki; Nakagawa, Hidehiko; Hasegawa, Makoto; Sasaki, Ryuzo; Mizukami, Tamio; Miyata, Naoki Journal of Medicinal Chemistry, 2010 , vol. 53, # 15 p. 5629 - 5638

 Synonyms

D4078
methyl 3-{[9-(dimethylamino)nonanoyl](hydroxy)amino}propanoate
NCDM-32b
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