DS-6930
Modify Date: 2025-08-25 17:36:04
DS-6930 structure
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Common Name | DS-6930 | ||
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| CAS Number | 1242328-82-0 | Molecular Weight | 403.438 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H21N3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DS-6930DS-6930 (DS 6930, DS6930) is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%; significantly recruits several cofactors, such as RIP140 and PGC1, in cofactor recruitment assays; demonstrateshigh PPARγ agonist potency with robust plasma glucose reduction, maintains diminished PPARγ-related adverse effects upon toxicological evaluation in vivo, and demonstrated no hepatotoxicity. Diabetes Discontinued |
| Name | DS-6930 |
|---|
| Description | DS-6930 (DS 6930, DS6930) is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%; significantly recruits several cofactors, such as RIP140 and PGC1, in cofactor recruitment assays; demonstrateshigh PPARγ agonist potency with robust plasma glucose reduction, maintains diminished PPARγ-related adverse effects upon toxicological evaluation in vivo, and demonstrated no hepatotoxicity. Diabetes Discontinued |
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| References | References 1. Shinozuka T, et al. Bioorg Med Chem. 2018 Oct 1;26(18):5099-5117. 2. Shinozuka T, et al. Bioorg Med Chem. 2018 Oct 1;26(18):5079-5098. View Related Products by Target PPAR Diabetes |
| Molecular Formula | C23H21N3O4 |
|---|---|
| Molecular Weight | 403.438 |
| InChIKey | NVXINLRTOZISKL-UHFFFAOYSA-L |
| SMILES | Cc1cnc(Oc2ccc3nc(COc4cccc(C(=O)[O-])c4)n(C)c3c2)c(C)c1.Cc1cnc(Oc2ccc3nc(COc4cccc(C(=O)[O-])c4)n(C)c3c2)c(C)c1.[Ca+2] |