1242328-82-0
1242328-82-0 structure
- Name: DS-6930
- Chemical Name: DS-6930
- CAS Number: 1242328-82-0
- Molecular Formula: C23H21N3O4
- Molecular Weight: 403.438
- Create Date: 2020-01-20 13:01:55
- Modify Date: 2025-08-25 17:36:04
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DS-6930 (DS 6930, DS6930) is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%; significantly recruits several cofactors, such as RIP140 and PGC1, in cofactor recruitment assays; demonstrateshigh PPARγ agonist potency with robust plasma glucose reduction, maintains diminished PPARγ-related adverse effects upon toxicological evaluation in vivo, and demonstrated no hepatotoxicity. Diabetes Discontinued
| Name | DS-6930 |
|---|
| Description | DS-6930 (DS 6930, DS6930) is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%; significantly recruits several cofactors, such as RIP140 and PGC1, in cofactor recruitment assays; demonstrateshigh PPARγ agonist potency with robust plasma glucose reduction, maintains diminished PPARγ-related adverse effects upon toxicological evaluation in vivo, and demonstrated no hepatotoxicity. Diabetes Discontinued |
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| References | References 1. Shinozuka T, et al. Bioorg Med Chem. 2018 Oct 1;26(18):5099-5117. 2. Shinozuka T, et al. Bioorg Med Chem. 2018 Oct 1;26(18):5079-5098. View Related Products by Target PPAR Diabetes |
| Molecular Formula | C23H21N3O4 |
|---|---|
| Molecular Weight | 403.438 |