VU0364739
Modify Date: 2025-09-24 12:18:39
VU0364739 structure
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Common Name | VU0364739 | ||
|---|---|---|---|---|
| CAS Number | 1244639-78-8 | Molecular Weight | 446.52 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H27FN4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of VU0364739VU0364739 is a selective PLD2 inhibitor (IC50: 22 nM). VU0364739 decreases cancer cell proliferation[1]. |
| Name | N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]-ethyl]-2-naphthalenecarboxamide |
|---|---|
| Synonym | More Synonyms |
| Description | VU0364739 is a selective PLD2 inhibitor (IC50: 22 nM). VU0364739 decreases cancer cell proliferation[1]. |
|---|---|
| Related Catalog | |
| Target |
PLD[1] |
| References |
| Molecular Formula | C26H27FN4O2 |
|---|---|
| Molecular Weight | 446.52 |
| Exact Mass | 446.21200 |
| PSA | 64.68000 |
| LogP | 3.85980 |
| InChIKey | MSTXJJGAXXJCBY-UHFFFAOYSA-N |
| SMILES | O=C(NCCN1CCC2(CC1)C(=O)NCN2c1cccc(F)c1)c1ccc2ccccc2c1 |
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Name: Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (...
Source: NCGC
External Id: IP6K1-p1
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu...
Source: NCGC
External Id: CYP3A4437
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Name: Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu...
Source: NCGC
External Id: CYP2D6395
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Name: Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu...
Source: NCGC
External Id: CYP2C9536
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Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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Name: Human PLD2 (Hydrolases)
Source: IUPHAR-DB
Target: PLD2 (Hydrolases) [Homo sapiens]
External Id: 1434_Human
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Name: A screen for small molecules that modulate mitochondrial supercomplex formation
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1482
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Name: Primary qHTS for Identification of Calcium Integrin Binding Protein 1 (CIB1) Competit...
Source: NCGC
External Id: CIB1-p1-p2
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Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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| N-(2-(1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5 ]decan-8-yl)ethyl)-2-naphthamide |
| N-(2-(1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide |
| N-[2-[1-(3-FLUOROPHENYL)-4-OXO-1,3,8-TRIAZASPIRO[4.5]DEC-8-YL]ETHYL]-2-NAPHTHALENECARBOXAMIDE |