Furaltadone-d8

Modify Date: 2024-01-09 23:16:32

Furaltadone-d8 Structure
Furaltadone-d8 structure
Common Name Furaltadone-d8
CAS Number 1246832-89-2 Molecular Weight 332.34
Density N/A Boiling Point N/A
Molecular Formula C13H8D8N4O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Furaltadone-d8


Furaltadone-d8 (Altafur-d8) is the deuterium labeled Furaltadone. Furaltadone, a nitrofuran drug, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci [1][2].

 Names

Name Furaltadone-d8

 Furaltadone-d8 Biological Activity

Description Furaltadone-d8 (Altafur-d8) is the deuterium labeled Furaltadone. Furaltadone, a nitrofuran drug, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci [1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. A.Rampling(Dr.), et al. The effect of furaltadone, a nitrofuran drug, on experimental infections of chickens with salmonella enteritidis phage Type 4. Pathology Volume 25, Supplement 1, 1993, Page 22.

[3]. William R. McCabe, et al. Furaltadone — A Critical Evaluation of Clinical and Laboratory Studies. N Engl J Med 1960; 263:927-934.

 Chemical & Physical Properties

Molecular Formula C13H8D8N4O6
Molecular Weight 332.34