Furaltadone

Modify Date: 2024-01-02 11:27:17

Furaltadone structure	Common Name	Furaltadone
	CAS Number	139-91-3	Molecular Weight	324.289
	Density	1.6±0.1 g/cm3	Boiling Point	461.4±55.0 °C at 760 mmHg
	Molecular Formula	C₁₃H₁₆N₄O₆	Melting Point	206ºC (dec.)
	MSDS	Chinese USA	Flash Point	232.8±31.5 °C
	Symbol	GHS07	Signal Word	Warning

Use of Furaltadone

Furaltadone, a nitrofuran drug, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci [1][2].

Name	furaltadone
Synonym	More Synonyms

Description	Furaltadone, a nitrofuran drug, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci [1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. A.Rampling(Dr.), et al. The effect of furaltadone, a nitrofuran drug, on experimental infections of chickens with salmonella enteritidis phage Type 4. Pathology Volume 25, Supplement 1, 1993, Page 22. [2]. William R. McCabe, et al. Furaltadone — A Critical Evaluation of Clinical and Laboratory Studies. N Engl J Med 1960; 263:927-934.

Description

Furaltadone, a nitrofuran drug, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci [1][2].

Related Catalog

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

References

[1]. A.Rampling(Dr.), et al. The effect of furaltadone, a nitrofuran drug, on experimental infections of chickens with salmonella enteritidis phage Type 4. Pathology Volume 25, Supplement 1, 1993, Page 22.

[2]. William R. McCabe, et al. Furaltadone — A Critical Evaluation of Clinical and Laboratory Studies. N Engl J Med 1960; 263:927-934.

Density	1.6±0.1 g/cm3
Boiling Point	461.4±55.0 °C at 760 mmHg
Melting Point	206ºC (dec.)
Molecular Formula	C₁₃H₁₆N₄O₆
Molecular Weight	324.289
Flash Point	232.8±31.5 °C
Exact Mass	324.106995
PSA	113.33000
LogP	-0.84
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.669
Storage condition	2-8°C

Furaltadone MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RQ3620000

CHEMICAL NAME :: 2-Oxazolidinone, 5-(morpholinomethyl)-3-((5-nitrofurfurylidene)amino)-

CAS REGISTRY NUMBER :: 139-91-3

BEILSTEIN REFERENCE NO. :: 0363627

LAST UPDATED :: 199612

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C13-H16-N4-O6

MOLECULAR WEIGHT :: 324.33

WISWESSER LINE NOTATION :: T5OJ BNW E1UN- AT5NVOTJ D1- AT6N DOTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Behavioral - antipsychotic Lungs, Thorax, or Respiration - respiratory depression Kidney, Ureter, Bladder - other changes in urine composition

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Microorganism - not otherwise specified

DOSE/DURATION :: 5 mg/L

REFERENCE :: CUMIDD Current Microbiology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1978- Volume(issue)/page/year: 10,19,1984

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R22
Safety Phrases	3-26
RIDADR	UN 3249
WGK Germany	3
RTECS	RQ3620000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2934992000

5-Nitrofuraldehyde

CAS#:698-63-5

AMOZ

CAS#:43056-63-9

Furaltadone

CAS#:139-91-3

Literature: Pharmaceutical Chemistry Journal, , # 11 p. 651 - 652 Khimiko-Farmatsevticheskii Zhurnal, , # 11 p. 47 - 49

5-Nitrofuraldehyde

CAS#:698-63-5

Furaltadone

CAS#:139-91-3

Literature: US2802002 , ;

Precursor 2
CAS#:698-63-5 5-Nitrofuraldehyde CAS#:43056-63-9 AMOZ
DownStream 0

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Elucidating the regulon of multidrug resistance regulator RarA in Klebsiella pneumoniae.

Antimicrob. Agents Chemother. 57(4) , 1603-9, (2013)

RarA is an AraC-type regulator in Klebsiella pneumoniae, which, when overexpressed, confers a low-level multidrug-resistant (MDR) phenotype linked to the upregulation of both the acrAB and oqxAB efflu...

Development of a competitive ELISA for the detection of a furaltadone marker residue, 3-amino-5-morpholinomethyl-2-oxazolidinone (AMOZ), in cultured fish samples.

J. Vet. Med. Sci. 74(11) , 1439-46, (2012)

This report describes an enzyme-linked immunosorbent assay (ELISA) for tissue-bound metabolite 3-amino-5-morpholinomethyl-2-oxazolidinone (AMOZ) and the application to residue analysis in cultured fis...

Cloning, expression, purification, and characterization of a novel single-chain variable fragment antibody against the 2-nitrobenzaldehyde derivative of a furaltadone metabolite in Escherichia coli.

Protein Expr. Purif. 84(1) , 140-6, (2012)

Furaltadone is an illicit veterinary drug that shows toxic, carcinogenic, and mutagenic effects, as does its metabolite 3-amino-5-morpholinomethyl-2-oxazolidone (AMOZ)(1). Recombinant antibodies with ...

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Otifuril

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Unifur

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Ultrafur

VALSYN

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Purity: 98.0%
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Furaltadone

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