Ajugamarin L2

Modify Date: 2025-08-21 17:04:31

Ajugamarin L2 Structure
Ajugamarin L2 structure
 Common Name Ajugamarin L2
CAS Number 124961-67-7 Molecular Weight 432.55000
Density 1.19g/cm3 Boiling Point 592ºC at 760 mmHg
Molecular Formula C25H36O6 Melting Point N/A
MSDS N/A Flash Point 196.5ºC

 Use of Ajugamarin L2


Ajudecunoid A is nature product that could be isolated from Ajuga decumbens. Ajudecunoid A inhibits RANKL-Induced osteoclastogenesis[1].

 Names

Name [(4aR,5S,7R,8S,8aR)-5-hydroxy-7,8-dimethyl-8-[2-(5-oxo-2H-furan-3-yl)ethyl]spiro[2,3,5,6,7,8a-hexahydro-1H-naphthalene-4,2'-oxirane]-4a-yl]methyl (E)-2-methylbut-2-enoate
Synonym More Synonyms

 Ajugamarin L2 Biological Activity

Description Ajudecunoid A is nature product that could be isolated from Ajuga decumbens. Ajudecunoid A inhibits RANKL-Induced osteoclastogenesis[1].
Related Catalog
In Vitro Ajudecunoid A (compound 1; 3 and 10 μM; 48 h) 以浓度依赖性方式抑制 RANKL 诱导的破骨细胞生成[1]。 Cell Viability Assay[1] Cell Line: Osteoclastogenesis Concentration: 3 and 10 Μm Incubation Time: 48 hours Result: Inhibited RANKL-induced osteoclastogenesis in a concentration dependent manner.
References

[1]. Wang H, et, al. Diterpenoids from the Whole Plants of Ajuga nipponensis and Their Inhibition of RANKL-Induced Osteoclastogenesis. Chem Biodivers. 2021 Jan;18(1):e2000780.  

 Chemical & Physical Properties

Density 1.19g/cm3
Boiling Point 592ºC at 760 mmHg
Molecular Formula C25H36O6
Molecular Weight 432.55000
Flash Point 196.5ºC
Exact Mass 432.25100
PSA 85.36000
LogP 3.72170
Vapour Pressure 1.76E-16mmHg at 25°C
Index of Refraction 1.553
Water Solubility Very slightly soluble (0.48 g/L) (25 ºC)

 Synonyms

Ajugacumbin B
Ajugamarin L2
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[(1S)-2-[(1S,2R,4S,4aR,8aR)-4-acetyloxy-4a-(hydroxymethyl)-1,2-dimethylspiro[3,4,6,7,8,8a-hexahydro-2H-naphthalene-5,2'-oxirane]-1-yl]-1-(5-oxo-2H-furan-3-yl)ethyl] (2S)-2-methylbutanoate
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