(±)-Usnic acid

Modify Date: 2024-01-02 06:06:07

(±)-Usnic acid structure	Common Name	(±)-Usnic acid
	CAS Number	125-46-2	Molecular Weight	344.315
	Density	1.5±0.1 g/cm3	Boiling Point	594.8±50.0 °C at 760 mmHg
	Molecular Formula	C₁₈H₁₆O₇	Melting Point	200°C
	MSDS	Chinese USA	Flash Point	219.1±23.6 °C

Use of (±)-Usnic acid

Usnic acid, a lichen-derived secondary metabolite, has a unique dibenzofuran skeleton. Usnic acid has excellent anticancer and antimicrobial properties. Usnic acid significantly inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1[1].

Name	usnic acid
Synonym	More Synonyms

Description	Usnic acid, a lichen-derived secondary metabolite, has a unique dibenzofuran skeleton. Usnic acid has excellent anticancer and antimicrobial properties. Usnic acid significantly inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Kim KJ, et al. Effect of Usnic Acid on Osteoclastogenic Activity. J Clin Med. 2018 Oct 12;7(10). pii: E345.

Density	1.5±0.1 g/cm3
Boiling Point	594.8±50.0 °C at 760 mmHg
Melting Point	200°C
Molecular Formula	C₁₈H₁₆O₇
Molecular Weight	344.315
Flash Point	219.1±23.6 °C
Exact Mass	344.089600
PSA	117.97000
LogP	2.68
Vapour Pressure	0.0±1.7 mmHg at 25°C
Index of Refraction	1.643
Storage condition	2-8C

(±)-Usnic acid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HP5270000

CHEMICAL NAME :: 1,3(2H,9bH)-dibenzofurandione, 2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-

CAS REGISTRY NUMBER :: 125-46-2

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C18-H16-O7

MOLECULAR WEIGHT :: 344.34

WISWESSER LINE NOTATION :: T B656 CV EV HO FU BHT&&J B1 DV1 JV1 KQ L1 MQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 75 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Mammal - species unspecified Cells - not otherwise specified

DOSE/DURATION :: 3750 ug/L

REFERENCE :: PHMCAA Pharmacologist. (American Soc. for Pharmacology and Experimental Therapeutics, 9650 Rockville Pike, Bethesda, MD 20014) V.1- 1959- Volume(issue)/page/year: 12,280,1970

Hazard Codes	Xn:Harmful;
Risk Phrases	R22
Safety Phrases	S22-S24/25
RTECS	HP5270000
HS Code	2917399090

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Usnic acid

MFCD00065294

EINECS 231-456-0

(±)-Usnic acid

2,6-Diacetyl-7,9-dihydroxy-8,9b-dimethyldibenzo[b,d]furan-1,3(2H,9bH)-dione

2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyldibenzofuran-1,3-dione

1,3(2H,9bH)-Dibenzofurandione, 2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (±)-Usnic acid
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: (±)-Usnic acid
Price: ￥248.0/20mg
Purity: 98.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

Get all suppliers and price by the below link:

(±)-Usnic acid suppliers

Price: ￥500/5 mg

Reference only. check more (±)-Usnic acid price

(±)-Usnic acid

Use of (±)-Usnic acid

Names

(±)-Usnic acid Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Customs

Synonyms