(±)-Usnic acid
Modify Date: 2026-07-23 19:22:42
(±)-Usnic acid structure
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Common Name | (±)-Usnic acid | ||
|---|---|---|---|---|
| CAS Number | 125-46-2 | Molecular Weight | 344.315 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 594.8±50.0 °C at 760 mmHg | |
| Molecular Formula | C18H16O7 | Melting Point | 200°C | |
| MSDS | Chinese USA | Flash Point | 219.1±23.6 °C | |
Use of (±)-Usnic acidUsnic acid, a lichen-derived secondary metabolite, has a unique dibenzofuran skeleton. Usnic acid has excellent anticancer and antimicrobial properties. Usnic acid significantly inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1[1]. |
| Name | usnic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Usnic acid, a lichen-derived secondary metabolite, has a unique dibenzofuran skeleton. Usnic acid has excellent anticancer and antimicrobial properties. Usnic acid significantly inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1[1]. |
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| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 594.8±50.0 °C at 760 mmHg |
| Melting Point | 200°C |
| Molecular Formula | C18H16O7 |
| Molecular Weight | 344.315 |
| Flash Point | 219.1±23.6 °C |
| Exact Mass | 344.089600 |
| PSA | 117.97000 |
| LogP | 2.68 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.643 |
| InChIKey | CUCUKLJLRRAKFN-UHFFFAOYSA-N |
| SMILES | CC(=O)c1c(O)c(C)c(O)c2c1OC1=CC(=O)C(C(C)=O)C(=O)C12C |
| Storage condition | 2-8C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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| Hazard Codes | Xn:Harmful; |
|---|---|
| Risk Phrases | R22 |
| Safety Phrases | S22-S24/25 |
| RTECS | HP5270000 |
| HS Code | 2917399090 |
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Name: ERK5 transcriptional activity HTS
Source: 24565
Target: N/A
External Id: ERK5 transcriptional activity-HTS
|
|
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100
|
|
Name: qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primar...
Source: NCGC
Target: 67.9K protein [Vaccinia virus]
External Id: Vaccinia-p2mCherry
|
|
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101
|
|
Name: Spectrum HTS for Inhibitors of Aerobactin Synthetase IucA
Source: 23265
Target: IucA Synthetase from hypervirulent Klebsiella pneumoniae hvKP1
External Id: IucA Pilot Assay Spectrum Library
|
|
Name: The chemical genetic matrix (CGM) dataset as reported in Wildenhain et al. (2015) Pre...
Source: 11924
Target: N/A
External Id: CGM data for Cell Systems paper Dec 2015
|
|
Name: qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary ...
Source: NCGC
Target: 67.9K protein [Vaccinia virus]
External Id: Vaccinia-p2Venus
|
|
Name: Cell cycle arrest in human HeLa cells assessed as accumulation of cells at G2/M phase...
Source: ChEMBL
Target: HeLa
External Id: CHEMBL4336073
|
|
Name: qHTS for Inhibitors of binding or entry into cells for Marburg Virus
Source: NCGC
Target: gene 4 small orf - Marburg virus
External Id: VSVM-OFFLINE
|
|
Name: qHTS for Inhibitors of binding or entry into cells for Lassa Virus
Source: NCGC
Target: N/A
External Id: VSVL-OFFLINE
|
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| Usnic acid |
| MFCD00065294 |
| EINECS 231-456-0 |
| (±)-Usnic acid |
| 2,6-Diacetyl-7,9-dihydroxy-8,9b-dimethyldibenzo[b,d]furan-1,3(2H,9bH)-dione |
| 2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyldibenzofuran-1,3-dione |