Pleuromutilin structure
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Common Name | Pleuromutilin | ||
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CAS Number | 125-65-5 | Molecular Weight | 378.502 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 482.8±45.0 °C at 760 mmHg | |
Molecular Formula | C22H34O5 | Melting Point | 170-171ºC | |
MSDS | Chinese USA | Flash Point | 158.7±22.2 °C |
Use of Pleuromutilinpleuromutilin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria. |
Name | Pleuromutilin |
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Synonym | More Synonyms |
Description | pleuromutilin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria. |
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Related Catalog | |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 482.8±45.0 °C at 760 mmHg |
Melting Point | 170-171ºC |
Molecular Formula | C22H34O5 |
Molecular Weight | 378.502 |
Flash Point | 158.7±22.2 °C |
Exact Mass | 378.240631 |
PSA | 83.83000 |
LogP | 2.63 |
Vapour Pressure | 0.0±2.8 mmHg at 25°C |
Index of Refraction | 1.538 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Hazard Codes | Xi |
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RIDADR | NONH for all modes of transport |
RTECS | MC5408000 |
HS Code | 2918199090 |
~% Pleuromutilin CAS#:125-65-5 |
Literature: Journal of the American Chemical Society, , vol. 111, # 21 p. 8284 - 8286 |
~% Pleuromutilin CAS#:125-65-5 |
Literature: Journal of the American Chemical Society, , vol. 111, # 21 p. 8284 - 8286 |
~% Pleuromutilin CAS#:125-65-5 |
Literature: Journal of the American Chemical Society, , vol. 111, # 21 p. 8284 - 8286 |
~% Pleuromutilin CAS#:125-65-5 |
Literature: Journal of the American Chemical Society, , vol. 111, # 21 p. 8284 - 8286 |
HS Code | 2918199090 |
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Summary | 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
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Antimicrob. Agents Chemother. 53 , 3589-91, (2009) A novel ABC transporter gene, vga(C), was identified on the 14,365-bp multiresistance plasmid pKKS825 in a porcine methicillin (meticillin)-resistant Staphylococcus aureus isolate of sequence type 398... |
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Design, synthesis, and antibacterial activity of novel pleuromutilin derivatives bearing an amino thiazolyl ring.
Arch. Pharm. (Weinheim) 345(8) , 638-46, (2012) A series of novel pleuromutilin derivatives containing the amino thiazolyl ring were designed, synthesized, and evaluated for their antibacterial activities in vitro against Gram-positive clinical bac... |
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Single 23S rRNA mutations at the ribosomal peptidyl transferase centre confer resistance to valnemulin and other antibiotics in Mycobacterium smegmatis by perturbation of the drug binding pocket.
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Pleuromulin |
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EINECS 204-747-5 |
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