Biotin-PEG3-NHS ester

Modify Date: 2024-01-11 06:56:39

Biotin-PEG3-NHS ester Structure
Biotin-PEG3-NHS ester structure
Common Name Biotin-PEG3-NHS ester
CAS Number 1253286-56-4 Molecular Weight 544.618
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C23H36N4O9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG3-NHS ester


Biotin-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.

 Names

Name N-{2-[2-(2-{3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethoxy)ethoxy]ethyl}-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide
Synonym More Synonyms

 Biotin-PEG3-NHS ester Biological Activity

Description Biotin-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C23H36N4O9S
Molecular Weight 544.618
Exact Mass 544.220276
LogP -2.93
Index of Refraction 1.574

 Synonyms

MFCD11974977
N-{2-[2-(2-{3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethoxy)ethoxy]ethyl}-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide
1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-[2-[2-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]ethoxy]ethoxy]ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)-
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