Propargyl-PEG3-NHS ester
Modify Date: 2025-09-03 19:42:21
Propargyl-PEG3-NHS ester structure
|
Common Name | Propargyl-PEG3-NHS ester | ||
|---|---|---|---|---|
| CAS Number | 1428629-71-3 | Molecular Weight | 313.303 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 427.2±55.0 °C at 760 mmHg | |
| Molecular Formula | C14H19NO7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 212.1±31.5 °C | |
Use of Propargyl-PEG3-NHS esterPropargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
| Name | 1-[(3-{2-[2-(2-Propyn-1-yloxy)ethoxy]ethoxy}propanoyl)oxy]-2,5-pyrrolidinedione |
|---|---|
| Synonym | More Synonyms |
| Description | Propargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| Target |
Cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
[1]. Earl F Albone, et al. Eribulin-based antibody-drug conjugates and methods of use. US20170252458A1. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 427.2±55.0 °C at 760 mmHg |
| Molecular Formula | C14H19NO7 |
| Molecular Weight | 313.303 |
| Flash Point | 212.1±31.5 °C |
| Exact Mass | 313.116150 |
| LogP | -1.96 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.507 |
| Hazard Codes | Xi |
|---|
| 1-[(3-{2-[2-(2-Propyn-1-yloxy)ethoxy]ethoxy}propanoyl)oxy]-2,5-pyrrolidinedione |
| 2,5-Pyrrolidinedione, 1-[1-oxo-3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]propoxy]- |
| MFCD23726610 |