AR-13324 (hydrochloride)
Modify Date: 2025-08-25 18:53:49
AR-13324 (hydrochloride) structure
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Common Name | AR-13324 (hydrochloride) | ||
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| CAS Number | 1253952-02-1 | Molecular Weight | 526.454 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H29Cl2N3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AR-13324 (hydrochloride)Netarsudil hydrochloride is a ROCK, and norepinephrine transporter inhibitor. Target: ROCKin vitro: AR-13324 is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive monkey eyes.[1] AR-13324 is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter.[2]in vivo: AR-13324 produces statistically significant lowering of episcleral venous pressure (EVP) in Dutch Belted (DB) rabbits. [3] |
| Name | SE030PF6VE |
|---|---|
| Synonym | More Synonyms |
| Description | Netarsudil hydrochloride is a ROCK, and norepinephrine transporter inhibitor. Target: ROCKin vitro: AR-13324 is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive monkey eyes.[1] AR-13324 is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter.[2]in vivo: AR-13324 produces statistically significant lowering of episcleral venous pressure (EVP) in Dutch Belted (DB) rabbits. [3] |
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| Related Catalog | |
| References |
| Molecular Formula | C28H29Cl2N3O3 |
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| Molecular Weight | 526.454 |
| Exact Mass | 525.158569 |
| InChIKey | LDKTYVXXYUJVJM-FBHGDYMESA-N |
| SMILES | Cc1ccc(C(=O)OCc2ccc(C(CN)C(=O)Nc3ccc4cnccc4c3)cc2)c(C)c1.Cl.Cl |
| Storage condition | -20℃ |
| Benzoic acid, 2,4-dimethyl-, [4-[(1S)-1-(aminomethyl)-2-(6-isoquinolinylamino)-2-oxoethyl]phenyl]methyl ester, hydrochloride (1:2) |
| 4-[(2S)-3-Amino-1-(6-isoquinolinylamino)-1-oxo-2-propanyl]benzyl 2,4-dimethylbenzoate dihydrochloride |
| NETARSUDIL DIHYDROCHLORIDE |
| SE030PF6VE |
| AR-13324 (hydrochloride) |