RQ-00311651
Modify Date: 2023-03-04 11:35:24
RQ-00311651 structure
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Common Name | RQ-00311651 | ||
|---|---|---|---|---|
| CAS Number | 1257116-00-9 | Molecular Weight | 405.374 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 655.8±55.0 °C at 760 mmHg | |
| Molecular Formula | C19H18F3N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 350.4±31.5 °C | |
Use of RQ-00311651RQ-00311651 is a novel T-type Ca2+ channel blocker, in distinct rodent models for neuropathic and visceral pain. RQ-00311651 strongly suppressed T currents when tested at holding potentials of -65 ～ -60 mV, but not -80 mV, in the Cav3.1- or Cav3.2-expressing cells. RQ-00311651 also inhibited high K-induced Ca signaling in those cells. |
| Name | (1S,2S)-2-(1H-Benzimidazol-2-yl)-N-{(1R)-1-[5-(2,2,2-trifluoroethoxy)-2-pyrazinyl]ethyl}cyclopropanecarboxamide |
|---|---|
| Synonym | More Synonyms |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 655.8±55.0 °C at 760 mmHg |
| Molecular Formula | C19H18F3N5O2 |
| Molecular Weight | 405.374 |
| Flash Point | 350.4±31.5 °C |
| Exact Mass | 405.141266 |
| LogP | 1.63 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.609 |
| (1S,2S)-2-(1H-Benzimidazol-2-yl)-N-{(1R)-1-[5-(2,2,2-trifluoroethoxy)-2-pyrazinyl]ethyl}cyclopropanecarboxamide |
| Cyclopropanecarboxamide, 2-(1H-benzimidazol-2-yl)-N-[(1R)-1-[5-(2,2,2-trifluoroethoxy)-2-pyrazinyl]ethyl]-, (1S,2S)- |