AZD 3676 structure
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Common Name | AZD 3676 | ||
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CAS Number | 1259929-13-9 | Molecular Weight | 378.476 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C22H26N4O2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of AZD 3676A novel potent, combined serotonin 5-HT1A and 5-HT1B receptor antagonist with Ki of 0.13 and 2.4 nM in brain homogenates, respectively; shows preclinical properties consistent with CNS drug potential, including nanomolar receptor affinity and efficacy in rodent models of learning and memory, shows the potential for the treatment of cognitive impairment in Alzheimer's disease. |
Name | AZD 3676 |
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Description | A novel potent, combined serotonin 5-HT1A and 5-HT1B receptor antagonist with Ki of 0.13 and 2.4 nM in brain homogenates, respectively; shows preclinical properties consistent with CNS drug potential, including nanomolar receptor affinity and efficacy in rodent models of learning and memory, shows the potential for the treatment of cognitive impairment in Alzheimer's disease. |
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References | References 1. Varnäs K, et al. J Pharmacol Exp Ther. 2016 Sep;358(3):464-71. View Related Products by Target Histamine Receptor |
Molecular Formula | C22H26N4O2 |
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Molecular Weight | 378.476 |